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The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Phytomedicine, 2022,Volume: 94
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming;  Sheng, Dekuan;  Lee, Simon Ming Yuen;  Leung, George Pak Heng;  Zhou, Guo Chun;  Li, Jingjing
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Journal of Biochemical and Molecular Toxicology, 2022
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
apoptosis  colon cancer  JNK1/2  psoralidin  ROS  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Pharmacological Research, 2021,Volume: 173
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling;  Yu, Jie;  Ai, Nana;  Lu, Jin Jian;  Ge, Wei;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Anticancer effects of asiatic acid against doxorubicin-resistant breast cancer cells via an AMPK-dependent pathway in vitro Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Zhu, Zhu;  Cui, Liao;  Yang, Jing;  Vong, Chi Teng;  Hu, Yuanjia;  Xiao, Jianbo;  Chan, Ging;  He, Zhiwei;  Zhong, Zhangfeng
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/12/08
Asiatic Acid  Breast Cancer  Centella Asiatica  Chemoresistance  Doxorubicin  
XDeep-AcPEP: Deep Learning Method for Anticancer Peptide Activity Prediction Based on Convolutional Neural Network and Multitask Learning Journal article
Journal of Chemical Information and Modeling, 2021,Volume: 61,Issue: 8,Page: 3789-3803
Authors:  Chen, Jiarui;  Cheong, Hong Hin;  Siu, Shirley W.I.
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Accuracy of Using a Patient-Derived Tumor Organoid Culture Model to Predict the Response to Chemotherapy Regimens in Stage IV Colorectal Cancer: A Blinded Study Journal article
Diseases of the Colon and Rectum, 2021,Page: 833-850
Authors:  Wang, Ting;  Pan, Wenjun;  Zheng, Hang;  Zheng, Hongping;  Wang, Zhejun;  Li, Jia J.;  Deng, Chuxia;  Yan, Jun
Favorite |  | TC[WOS]:5 TC[Scopus]:6 | Submit date:2022/05/13
Accuracy  Chemotherapy response  Colorectal cancer  Patient-derived tumor organoid  Predictive model  
Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells Journal article
Frontiers in Immunology, 2020,Volume: 11
Authors:  Huang, Yi Wen;  Lin, Chien Wei;  Pan, Pan;  Shan, Tianjiao;  Echeveste, Carla Elena;  Mo, Yue Yang;  Wang, Hsin Tzu;  Aldakkak, Mohammed;  Tsai, Susan;  Oshima, Kiyoko;  Yearsley, Martha;  Xiao, Jianbo;  Cao, Hui;  Sun, Chongde;  Du, Ming;  Bai, Weibin;  Yu, Jianhua;  Wang, Li Shu
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/12/06
Black Raspberries  Colorectal (Colon) Cancer  Human Clinical Trials  Natural Killer Cells  Smad4  
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/02
Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Dietary polyphenols for managing cancers: What have we ignored? Journal article
Trends in Food Science and Technology, 2020,Volume: 101,Page: 150-164
Authors:  Wu,Xu;  Li,Mingxing;  Xiao,Zhangang;  Daglia,Maria;  Dragan,Simona;  Delmas,Dominique;  Vong,Chi Teng;  Wang,Yitao;  Zhao,Yueshui;  Shen,Jing;  Nabavi,Seyed Mohammad;  Sureda,Antoni;  Cao,Hui;  Simal-Gandara,Jesus;  Wang,Mingfu;  Sun,Chongde;  Wang,Shengpeng;  Xiao,Jianbo
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2021/03/02
Anti-cancer Activity  Bioavailability  Dietary Polyphenols  Metabolites  Microbiota  Stability