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Camellia nitidissima Chi extract promotes adult hippocampal neurogenesis and attenuates chronic corticosterone-induced depressive behaviours through regulating Akt/GSK3β/CREB signaling pathway Journal article
Journal of Functional Foods, 2022,Volume: 95,Page: 105199
Authors:  Tsoi, Bun;  Gao, Chong;  Yan, Shenyu;  Du, Qiaohui;  Yu, Hua;  Li, Peng;  Deng, Jiagang;  Shen, Jiangang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/29
Hederagenin stimulated AKT activation and rescued PC12 cells from corticosterone injury Conference paper
中国药理学会表观遗传药理专业委员会. 2021年医药前沿-第六届表观遗传与生物医药研发学术大会
Authors:  Zheng, W.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/31
Hederagenin  Corticosterone  PC12 cells  AKT Pathway  Depression  
Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Lin, Ruohong;  Liu, Linlin;  Silva, Marta;  Fang, Jiankang;  Zhou, Zhiwei;  Wang, Haitao;  Xu, Jiangping;  Li, Tiejun;  Zheng, Wenhua
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/12/08
Akt  Corticosterone  Depression  Hederagenin  Pathway  Pc12 Cells  Pi3k  
AKT activation is involved in the protective effect of hederagenin on PC12 cells against corticosterone injury Conference paper
7th macau symposium on Biomedical Science
Authors:  Lin, R.;  Zheng, W.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/31
AKT activation  hederagenin  PC12 cells  corticosterone injury  
Hederagenin stimulated AKT activation and rescued PC12 cells from corticosterone injury Conference paper
The 4th National Basic Research Symposium on the Quality of Traditional Chinese Medicine 2020
Authors:  Lin, R.;  Zheng, W.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/31
Hederagenin  AKT  PC12 cells  corticosterone injury  
FoxO3a inhibits the expression of neuropeptide W in neuronal cells and rat hypothalamus and its effect on the hypothalamic-pituitary-adrenal (HPA) axis Conference paper
The 4th National Basic Research Symposium on the Quality of Traditional Chinese Medicine 2020, N/A, 2020-11-1
Authors:  Yang, C.;  Zheng, W.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/31
Foxo3a  Neuropeptide w  Hypothalamic-pituitary-adrenal  
Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model Journal article
Phytomedicine, 2020,Volume: 67
Authors:  Chi,Liandi;  Khan,Imran;  Lin,Zibei;  Zhang,Jiwen;  Lee,M. Y.Simon;  Leong,Waikit;  Hsiao,W. L.Wendy;  Zheng,Ying
Favorite |  | TC[WOS]:17 TC[Scopus]:27 | Submit date:2021/03/01
Behavioral Tests  Chronic Unpredictable Mild Stress (Cums)  Gut Microbiota  Inulin-type Fructo-oligosaccharides (Foss)  
Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)  
Suppressive effects of the supercritical-carbon dioxide fluid extract of Chrysanthemum indicum on chronic unpredictable mild stress-induced depressive-like behavior in mice Journal article
FOOD & FUNCTION, 2019,Volume: 10,Issue: 2,Page: 1212-1224
Authors:  Xiaoli Wu;  Benqin Tang;  Xian Liao;  Ziren Su;  Simon Ming-Yuen Lee;  Yefeng Cai;  Chuwen Li
Favorite |  | TC[WOS]:18 TC[Scopus]:16 | Submit date:2020/01/16
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite |  | TC[WOS]:22 TC[Scopus]:25 | Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection