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Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2021,Volume: 173,Page: 64-69
Authors:  Yu, Jie;  Zhong, Bingling;  Zhao, Lin;  Hou, Ying;  Wang, Xianzhe;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Nec-1  Nec-1s  Nqo1  Ripk1  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/09/17
Cell Death  Danshen  Noptosis  Nqo1  
A pharmacological review of dicoumarol: An old natural anticoagulant agent Journal article
Pharmacological Research, 2020,Volume: 160
Authors:  Sun,Chong;  Zhao,Wenwen;  Wang,Xumei;  Sun,Yinxiang;  Chen,Xiuping
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/01
Bioactivity  Dicoumarol  Pharmacokinetic  Side Effects  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by MAM Conference paper
Collection of 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Sun, W.;  Hou, Y.;  Zhang, Y.Y.;  Li, Z.W.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  necroptosis  glioma  
NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells Conference paper
Collection of The 2018 International Conference on the Pharmacology of Traditional Medicine of the Belt and Road Initiative
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Gao, H.W.;  Sun, W.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  glioblastomas  non-canonical necroptosis  NQO1  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by a natural product, 2-Methoxy-6-acetyl-7-methyljuglone (MAM) Conference paper
Collection The 6th Guangzhou International Symposium on Oncology
Authors:  Yu, J.;  Li, Z.W.;  Hou, Y.;  Yuan, R.Y.K.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  necroptosis  NQO1  ROS  RIP1/RIP3