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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
Topological Maps and Brain Computations From Low to High Journal article
Frontiers in Systems Neuroscience, 2022
Authors:  Sereno, Martin I.;  Sood, Mariam Reeny;  Huang, Ruey-Song
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Dysregulation of Human Somatic piRNA Expression in Parkinson’s Disease Subtypes and Stages Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 5,Page: 2469
Authors:  Zhang, Tianjiao;  Wong, Garry
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Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Acta Pharmacologica Sinica, 2022
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Guan, Xin jie;  Kan, Yu xuan;  Xie, Wen jian;  Zhao, Chen liang;  Cheung, King ho;  Lu, Jia hong;  Tan, Jie qiong;  Zhang, Hong jie;  Song, Ju xian;  Li, Min
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  Mpp++++  Oxindole Alkaloid  Parkinson’s Disease  Pi3p  Pik3c3 Complex  
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021,Volume: 1867,Issue: 10
Authors:  Huang, Xiaobing;  Wang, Changliang;  Chen, Liang;  Zhang, Tianjiao;  Leung, Ka Lai;  Wong, Garry
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Amyloid β  Lewy Body Dementia  Lipid Metabolism  Lysosome Function  Α-synuclein  
Synergistic Photothermal and Chemical Therapy by Smart Dual-Functional Graphdiyne Nanosheets for Treatment of Parkinson's Disease Journal article
Advanced Therapeutics, 2021,Volume: 4,Issue: 7,Page: 2100082
Authors:  Li, Tianzhong;  Liu, Yao;  Bao, Wenli;  Luo, Jingshan;  Gao, Lingfeng;  Chen, Xiaojia;  Wang, Shengpeng;  Yu, Jiangtian;  Ge, Yanqi;  Zhang, Bin;  Xie, Ni;  Xie, Zhongjian;  Chen, Tongkai;  Zhang, Han
Favorite |  | TC[WOS]:12 TC[Scopus]:10 | Submit date:2021/12/08
Drug Delivery  Graphdiyne  Minocycline  Parkinson's Disease  Photothermal Therapy  
Engineered exosomes: Desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies Journal article
Theranostics, 2021,Volume: 11,Issue: 18,Page: 8926-8944
Authors:  Xu, Meng;  Feng, Tao;  Liu, Bowen;  Qiu, Fen;  Xu, Youhua;  Zhao, Yonghua;  Zheng, Ying
Adobe PDF | Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2022/05/13
Administration Routes  Brain Targeting  Cerebrovascular Disease  Engineered Exosomes  Neurological Disorders  Tracking  
无权访问的条目 Journal article
Authors:  Yu,Qian;  Zou,Liye;  Kong,Zhaowei;  Yang,Lin
Favorite |  | TC[WOS]:4 TC[Scopus]:8 | Submit date:2020/11/06
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther;  Lakso,Merja;  Wong,Garry
Favorite |  | TC[WOS]:8 TC[Scopus]:6 | Submit date:2021/03/02
C. Elegans  Lewy Body Dementia  Neurodegeneration  Parkinson's Disease  Tdp-1/tdp-43  Tdp-43  Α-synuclein  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han,Chaojun;  Yan,Pengju;  He,Tao;  Cheng,Junjie;  Zheng,Wenhua;  Zheng,Long Tai;  Zhen,Xuechu
Favorite |  | TC[WOS]:14 TC[Scopus]:16 | Submit date:2021/03/04
Dopaminergic Neuron  Microglia  Neuroinflammation  Nf-κb  Phlda1  Traf6  Ubiquitination