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Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin Journal article
eFood, 2022,Volume: 3,Issue: e3
Authors:  Ruting ZHONG;  Mohamed A. Farag;  Meiwan Che;  Chengwei He;  Jianbo Xiao
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/07/29
Bioactivities  Fisetin  Molecular Mechanism  Pharmacokinetics  Structure–activity Relationship  
The development of small-molecule inhibitors targeting hexokinase 2 Journal article
Drug Discovery Today, 2022,Volume: 27,Issue: 9,Page: 2574-2585
Authors:  Shan, Wenying;  Zhou, Yan;  Tam, Kin Yip
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2022/08/05
Cancer Metabolism  Drug–target Binding  Hexokinase 2  Selective Inhibition  Structure-based Molecular Design  
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow Journal article
Nature Biomedical Engineering, 2022,Volume: 6,Issue: 1,Page: 76-93
Authors:  Xie, Chenglong;  Zhuang, Xu Xu;  Zheng WH(鄭文華);  Shen, Han Ming;  Lu, Jia Hong;  Fang, Evandro F
Adobe PDF | Favorite |  | TC[WOS]:39 TC[Scopus]:44 | Submit date：2022/12/12
Structural basis of ligand binding modes at the human formyl peptide receptor 2 Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Chen, Tong;  Xiong, Muya;  Zong, Xin;  Ge, Yunjun;  Zhang, Hui;  Wang, Mu;  Won Han, Gye;  Yi, Cuiying;  Ma, Limin;  Ye, Richard D.;  Xu, Yechun;  Zhao, Qiang;  Wu, Beili
Favorite |  | TC[WOS]:39 TC[Scopus]:39 | Submit date：2021/12/06
Reflections on treatment of COVID-19 with traditional Chinese medicine Journal article
Chinese Medicine, 2020,Volume: 15,Issue: 1
Authors:  Luo,Hua;  Gao,Yan;  Zou,Jian;  Zhang,Siyuan;  Chen,Hanbin;  Liu,Qiao;  Tan,Dechao;  Han,Yan;  Zhao,Yonghua;  Wang,Shengpeng
Adobe PDF | Favorite |  | TC[WOS]:34 TC[Scopus]:36 | Submit date：2021/03/02
Coronavirus  Covid-19  Prescriptions  Traditional Chinese Medicine  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View | Adobe PDF | Favorite |  | TC[WOS]:22 TC[Scopus]:25 | Submit date：2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
TNF Receptor Type II as an Emerging Drug Target for the Treatment of Cancer, Autoimmune Diseases, and Graft-Versus-Host Disease: Current Perspectives and In Silico Search for Small Molecule Binders Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Shaikh, Faraz;  He, Jiang;  Bhadra, Pratiti;  Chen, Xin;  Siu, Shirley W., I
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date：2018/10/30
Tnf Receptor Type Ii  Tnf  Regulatory t Cells  Virtual Screening  Drug Discovery  Mm-pbsa  
TNF receptor type II as an emerging drug target for the treatment of cancer, autoimmune diseases, and graft-versus-host disease: Current perspectives and in silico search for small molecule binders Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUN
Authors:  Shaikh F.;  He J.;  Bhadra P.;  Chen X.;  Siu S.W.
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date：2019/04/04
Drug Discovery  Mm-pbsa  Regulatory t Cells  Tnf  Tnf Receptor Type Ii  Virtual Screening  
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
Favorite |  | TC[WOS]:36 TC[Scopus]:38 | Submit date：2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine  
In silico target fishing for the potential targets and molecular mechanisms of baicalein as an antiparkinsonian agent: Discovery of the protective effects on nmda receptor-mediated neurotoxicity Journal article
Chemical Biology and Drug Design, 2013,Volume: 81,Issue: 6,Page: 675
Authors:  Gao L.;  Fang J.-S.;  Bai X.-Y.;  Zhou D.;  Wang Y.-T.;  Liu A.-L.;  Du G.-H.
Favorite |  | TC[WOS]:14 TC[Scopus]:22 | Submit date：2018/10/31
Baicalein  In Silico  N-methyl-d-aspartic Acid  Neurotoxicity  Parkinson's Disease  Target Fishing