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Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas Journal article
Journal of Translational Medicine, 2019,Volume: 17,Issue: 1
Authors:  Sun X.;  Liu X.;  Xia M.;  Shao Y.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:13 TC[Scopus]:11 | Submit date:2021/03/03
Biomarker  Drug Resistance  Glioma  Macrophages  Multicellular Gene Network  Prognostic Signature  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite |  | TC[WOS]:21 TC[Scopus]:21 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite |  | TC[WOS]:27 TC[Scopus]:27 | Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol Journal article
International Journal of Oncology, 2016,Volume: 49,Issue: 4,Page: 1576-1588
Authors:  Xu S.-W.;  Law B.Y.K.;  Mok S.W.F.;  Leung E.L.H.;  Fan X.X.;  Coghi P.S.;  Zeng W.;  Leung C.-H.;  Ma D.-L.;  Liu L.;  Wong V.K.W.
Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/11/06
Autophagy  Calcium  Celastrol  Epidermal Growth Factor Receptor  Gefitinib-resistant Lung Cancer  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang,Zheng;  Tam,Kin Y.
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2021/03/04
Dichloroacetate  Drug combination  Epidermal growth factor Receptor  Erlotinib  Gefitinib  Pyruvate dehydrogenase kinase  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase