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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date：2021/12/08
Drug Resistance  Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor  Non-small Cell Lung Cancer  Targeted Therapy  
Single-cell analyses reveal mechanisms of cancer stem cell maintenance and epithelial-mesenchymal transition in recurrent bladder cancer Journal article
Clinical Cancer Research, 2021,Volume: 27,Issue: 22,Page: 6265-6278
Authors:  Wang, Huanjun;  Mei, Yan;  Luo, Cheng;  Huang, Qun;  Wang, Zifeng;  Lu, Guan Ming;  Qin, Lili;  Sun, Zhun;  Huang, Chao Wen;  Yang, Zhi Wen;  Chen, Junxing;  Yin, Weiguo;  Qian, Chao Nan;  Zeng, Jianming;  Chen, Lingwu;  Leng, Qibin;  Guo1, Yan;  Jia, Guangshuai
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date：2021/12/08
Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:  Lei, Josh Haipeng;  Lee, Mi Hye;  Miao, Kai;  Huang, Zebin;  Yao, Zhicheng;  Zhang, Aiping;  Xu, Jun;  Zhao, Ming;  Huang, Zenan;  Zhang, Xin;  Chen, Si;  Jiaying, N. G.;  Feng, Yuzhao;  Xing, Fuqiang;  Chen, Ping;  Sun, Heng;  Chen, Qiang;  Xiang, Tingxiu;  Chen, Lin;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Brca1  Breast Cancer  Fgfr2 Inhibitor  Fgfr2-s252w  Tumor Slice Culture  
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells Journal article
Toxicology and Applied Pharmacology, 2021,Volume: 420
Authors:  Sun, Chong;  Liu, Rong;  Xia, Mengwei;  Hou, Ying;  Wang, Xumei;  Lu, Jin jian;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Emt  Lung Cancer  Metastasis  Nannocystin Ax  
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao;  Bao, Jiaolin;  Zeng, Jianming;  Hao, Wenhui;  Sun, Heng;  Wong, Ada Hang Heng;  Valecha, Monica Vishnu;  Yang, Eun Ju;  Su, Sek Man;  Choi, Tak Kan;  Liu, Shuiming;  Chan, Kin Iong;  Yang, Ling Lin;  Wu, Jingbo;  Miao, Kai;  Chen, Qiang;  Shim, Joong Sup;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/11/30
Sequential Release of Pooled siRNAs and Paclitaxel by Aptamer-Functionalized Shell-Core Nanoparticles to Overcome Paclitaxel Resistance of Prostate Cancer Journal article
ACS Applied Materials and Interfaces, 2021,Volume: 13,Issue: 12,Page: 13990-14003
Authors:  Guo, Qianqian;  Dong, Yang;  Zhang, Yanhua;  Fu, Hao;  Chen, Chuanrong;  Wang, Liting;  Yang, Xupeng;  Shen, Ming;  Yu, Jian;  Chen, Meiwan;  Zhang, Jiali;  Duan, Yourong
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date：2021/12/07
Aptamer  Combinational Therapy  Epithelial-mesenchymal Transition  Ptx-resistant Prostate Cancer  Sequential Release  
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:8 TC[Scopus]:7 | Submit date：2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
ceRNA Networks: The Backbone Role in Neoadjuvant Chemoradiotherapy Resistance/Sensitivity of Locally Advanced Rectal Cancer Journal article
Technology in cancer research & treatment, 2021,Volume: 20
Authors:  He, Lin;  Chang, Hao;  Qi, Yuhong;  Zhang, Bing;  Shao, Qiuju
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
competing endogenous RNAs  DNA damage repair  locally advanced rectal cancer  neoadjuvant chemoradiotherapy  
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Genes and Diseases, 2021
Authors:  Cheng, Shasha;  Yang, Guan Jun;  Wang, Wanhe;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date：2022/05/13
Cancer stem cells  CDK9-cyclin T1  Epithelial mesenchymal transition  Protein–protein interaction (PPI)  Triple-negative breast cancer (TNBC)