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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy
Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:
Zhao, Yuxin
;
Wang, Haiyong
;
He, Chengwei
Favorite
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TC[WOS]:
2
TC[Scopus]:
4
|
Submit date:2021/12/08
Drug Resistance
Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor
Non-small Cell Lung Cancer
Targeted Therapy
Single-cell analyses reveal mechanisms of cancer stem cell maintenance and epithelial-mesenchymal transition in recurrent bladder cancer
Journal article
Clinical Cancer Research, 2021,Volume: 27,Issue: 22,Page: 6265-6278
Authors:
Wang, Huanjun
;
Mei, Yan
;
Luo, Cheng
;
Huang, Qun
;
Wang, Zifeng
;
Lu, Guan Ming
;
Qin, Lili
;
Sun, Zhun
;
Huang, Chao Wen
;
Yang, Zhi Wen
;
Chen, Junxing
;
Yin, Weiguo
;
Qian, Chao Nan
;
Zeng, Jianming
;
Chen, Lingwu
;
Leng, Qibin
;
Guo1, Yan
;
Jia, Guangshuai
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TC[WOS]:
2
TC[Scopus]:
1
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Submit date:2021/12/08
Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy
Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:
Lei, Josh Haipeng
;
Lee, Mi Hye
;
Miao, Kai
;
Huang, Zebin
;
Yao, Zhicheng
;
Zhang, Aiping
;
Xu, Jun
;
Zhao, Ming
;
Huang, Zenan
;
Zhang, Xin
;
Chen, Si
;
Jiaying, N. G.
;
Feng, Yuzhao
;
Xing, Fuqiang
;
Chen, Ping
;
Sun, Heng
;
Chen, Qiang
;
Xiang, Tingxiu
;
Chen, Lin
;
Xu, Xiaoling
;
Deng, Chu Xia
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/11/30
Brca1
Breast Cancer
Fgfr2 Inhibitor
Fgfr2-s252w
Tumor Slice Culture
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells
Journal article
Toxicology and Applied Pharmacology, 2021,Volume: 420
Authors:
Sun, Chong
;
Liu, Rong
;
Xia, Mengwei
;
Hou, Ying
;
Wang, Xumei
;
Lu, Jin jian
;
Liu, Bo
;
Chen, Xiuping
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08
Emt
Lung Cancer
Metastasis
Nannocystin Ax
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics
Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:
Ding, Ren Bo
;
Chen, Ping
;
Rajendran, Barani Kumar
;
Lyu, Xueying
;
Wang, Haitao
;
Bao, Jiaolin
;
Zeng, Jianming
;
Hao, Wenhui
;
Sun, Heng
;
Wong, Ada Hang Heng
;
Valecha, Monica Vishnu
;
Yang, Eun Ju
;
Su, Sek Man
;
Choi, Tak Kan
;
Liu, Shuiming
;
Chan, Kin Iong
;
Yang, Ling Lin
;
Wu, Jingbo
;
Miao, Kai
;
Chen, Qiang
;
Shim, Joong Sup
;
Xu, Xiaoling
;
Deng, Chu Xia
Favorite
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TC[WOS]:
3
TC[Scopus]:
3
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Submit date:2021/11/30
Sequential Release of Pooled siRNAs and Paclitaxel by Aptamer-Functionalized Shell-Core Nanoparticles to Overcome Paclitaxel Resistance of Prostate Cancer
Journal article
ACS Applied Materials and Interfaces, 2021,Volume: 13,Issue: 12,Page: 13990-14003
Authors:
Guo, Qianqian
;
Dong, Yang
;
Zhang, Yanhua
;
Fu, Hao
;
Chen, Chuanrong
;
Wang, Liting
;
Yang, Xupeng
;
Shen, Ming
;
Yu, Jian
;
Chen, Meiwan
;
Zhang, Jiali
;
Duan, Yourong
Favorite
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TC[WOS]:
6
TC[Scopus]:
6
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Submit date:2021/12/07
Aptamer
Combinational Therapy
Epithelial-mesenchymal Transition
Ptx-resistant Prostate Cancer
Sequential Release
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing
Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:
Sun, Heng
;
Zeng, Jianming
;
Miao, Zhengqiang
;
Lei, Kuan Cheok
;
Huang, Chen
;
Hu, Lingling
;
Su, Sek Man
;
Chan, Un In
;
Miao, Kai
;
Zhang, Xu
;
Zhang, Aiping
;
Guo, Sen
;
Chen, Si
;
Meng, Ya
;
Deng, Min
;
Hao, Wenhui
;
Lei, Haipeng
;
Lin, Ying
;
Yang, Zhonglin
;
Tang, Dongjiang
;
Wong, Koon Ho
;
Zhang, Xiaohua Douglas
;
Xu, Xiaoling
;
Deng, Chu Xia
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/11/30
Brca1/BRCA1
Mammary tumor
Mrc2
Single cell RNA-seq
Tumor heterogeneity
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel
Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:
Wang,Haitao
;
Guo,Sen
;
Kim,Seung Jin
;
Shao,Fangyuan
;
Kei Ho,Joshua Wing
;
Wong,Kuan Un
;
Miao,Zhengqiang
;
Hao,Dapeng
;
Zhao,Ming
;
Xu,Jun
;
Zeng,Jianming
;
Wong,Koon Ho
;
Di,Lijun
;
Wong,Ada Hang Heng
;
Xu,Xiaoling
;
Deng,Chu Xia
Favorite
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TC[WOS]:
8
TC[Scopus]:
7
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Submit date:2021/03/02
Cisplatin
Metastasis
Neoadjuvant Therapy
Paclitaxel
Tgfβ
ceRNA Networks: The Backbone Role in Neoadjuvant Chemoradiotherapy Resistance/Sensitivity of Locally Advanced Rectal Cancer
Journal article
Technology in cancer research & treatment, 2021,Volume: 20
Authors:
He, Lin
;
Chang, Hao
;
Qi, Yuhong
;
Zhang, Bing
;
Shao, Qiuju
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
competing endogenous RNAs
DNA damage repair
locally advanced rectal cancer
neoadjuvant chemoradiotherapy
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells
Journal article
Genes and Diseases, 2021
Authors:
Cheng, Shasha
;
Yang, Guan Jun
;
Wang, Wanhe
;
Ma, Dik Lung
;
Leung, Chung Hang
Favorite
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TC[WOS]:
0
TC[Scopus]:
3
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Submit date:2022/05/13
Cancer stem cells
CDK9-cyclin T1
Epithelial mesenchymal transition
Protein–protein interaction (PPI)
Triple-negative breast cancer (TNBC)