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Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2020/09/16
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Phytomedicine, 2019,Volume: 52,Page: 32-39
Authors:  Zhang L.-L.;  Jiang X.-M.;  Huang M.-Y.;  Feng Z.-L.;  Chen X.;  Wang Y.;  Li H.;  Li A.;  Lin L.-G.;  Lu J.-J.
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2018/12/28
Epithelial-mesenchymal transition  Nagilactone E  Smad  TGF-β1  
Toosendanin, a natural product, inhibited TGF-β1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
Phytotherapy Research, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo,Weiwei;  Liu,Xin;  Sun,Wen;  Lu,Jin Jian;  Wang,Yitao;  Chen,Xiuping
Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2021/03/01
EMT  ERK1/2  lung cancer  Snail  toosendanin  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite |  | TC[WOS]:10 TC[Scopus]:12 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View | Adobe PDF | Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite |  | TC[WOS]:18 TC[Scopus]:17 | Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3