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Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Journal article
Expert Opinion on Therapeutic Patents, 2022,Volume: 32,Issue: 4,Page: 441-453
Authors:  Zhou, Yan;  Guo, Yizhen;  Tam, Kin Yip
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
cancer glucose metabolism  Cancer treatment patent  glycolytic inhibitor  hexokinase 2 (HK2)  lactate dehydrogenase A (LDHA)  pyruvate dehydrogenase kinase (PDK)  Warburg effect  
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy Journal article
International Journal of Biological Macromolecules, 2021,Volume: 193,Page: 1499-1506
Authors:  Yang, Guan Jun;  Wu, Jia;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2022/01/14
Leukemia  Modulators  Pyruvate Kinase M2  
Genome-wide differential expression profiling of lncRNAs and mRNAs in human induced pluripotent stem cell-derived endothelial cells exposed to e-cigarette extract Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:  Le, Hoai Huong Thi;  Liu, Chen wei;  Denaro, Philip;  Jousma, Jordan;  Shao, Ning Yi;  Rahman, Irfan;  Lee, Won Hee
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/01/14
E-cigarettes  Endothelial Dysfunction  Fatty Acid Oxidation  Ipsc-ecs  Lncrnas  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date:2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Regulation of energy metabolism in human pluripotent stem cells Journal article
Cellular and Molecular Life Sciences, 2021,Volume: 78,Issue: 24,Page: 8097-8108
Authors:  Liu, Weiwei;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Glycolysis  Insulin  Nutrient  Oxidative Phosphorylation  Oxygen  Ph  
Protocol for intracellular and extracellular metabolite detection in human embryonic stem cells Journal article
STAR Protocols, 2021,Volume: 2,Issue: 3
Authors:  Xu, Faxiang;  Song, Chengcheng;  Liu, Weiwei;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2021/12/08
Cell culture  Cell Differentiation  Flow Cytometry/Mass Cytometry  Metabolism  Metabolomics  Stem Cells  
Nuclear hkii–p-p53 (Ser15) interaction is a prognostic biomarker for chemoresponsiveness and glycolytic regulation in epithelial ovarian cancer Journal article
Cancers, 2021,Volume: 13,Issue: 14
Authors:  Han, Chae Young;  Patten, David A.;  Kim, Se Ik;  Lim, Jung Jin;  Chan, David W.;  Siu, Michelle K.Y.;  Han, Youngjin;  Carmona, Euridice;  Parks, Robin J.;  Lee, Cheol;  Di, Li Jun;  Lu, Zhen;  Chan, Karen K.L.;  Ku, Ja Lok;  Macdonald, Elizabeth A.;  Vanderhyden, Barbara C.;  Mes-Masson, Anne Marie;  Ngan, Hextan Y.S.;  Cheung, Annie N.Y.;  Song, Yong Sang;  Bast, Robert C.;  Harper, Mary Ellen;  Tsang, Benjamin K.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Cancer Metabolism  Chemoresistance  Epithelial Ovarian Cancer  Hexokinase Ii  P-p53 (Ser15)  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer Metabolism  Proliferation  Pyruvate Dehydrogenase Kinase  Structure-activity Relationship  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu,Puhua;  Zhou,Yan;  Guo,Yizhen;  Zhang,Shao Lin;  Tam,Kin Yip
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Journal of Cellular Physiology, 2021,Volume: 236,Issue: 2,Page: 981-996
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/03/02
Demethylation  Dhx33  Gadd45a  Glycolysis  Rna Helicase  Warburg Effect