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Disease-Modifying Activity of Huperzine A on Alzheimer’s Disease: Evidence from Preclinical Studies on Rodent Models Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 23
Authors:  Yan, Ye Piao;  Chen, Jia Yue;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/01/30
Alzheimer’s Disease  Animal Studies  Huperzine a  Meta-analysis  Preclinical Studies  Systematic Review  
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity Journal article
Fitoterapia, 2019,Volume: 139
Authors:  Feng,Zheling;  Chen,Shixin;  Wang,Wei;  Feng,Lu;  Dong,Yanyan;  Zou,Yiping;  Ke,Changqiang;  Tang,Chunping;  Yao,Sheng;  Zhang,Haiyan;  Gan,Lishe;  Ye,Yang;  Lin,Ligen
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date：2021/03/01
Ecd  Lycodine-type Alkaloids  Lycopodiaceae  Lycopodiastrum Casuarinoides  Td-dft  
Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis Journal article
Human Psychopharmacology, 2016,Page: 286-295
Authors:  Zheng W.;  Xiang Y.-Q.;  Li X.-B.;  Ungvari G.S.;  Chiu H.F.K.;  Sun F.;  D'Arcy C.;  Meng X.;  Xiang Y.-T.
Favorite |  | TC[WOS]:5 TC[Scopus]:9 | Submit date：2018/12/18
Antipsychotic  Cognitive Function  Huperzine a  Meta-analysis  Schizophrenic-spectrum Disorders  Systematic Review  
Huperzine A for treatment of cognitive impairment in major depressive disorder: a systematic review of randomized controlled trials Journal article
Shanghai Archives of Psychiatry, 2016,Volume: 28,Issue: 2,Page: 64-71
Authors:  Zheng W.;  Xiang Y.-Q.;  Ungvari G.S.;  Chiu H.F.;  Ng C.H.;  Wang Y.;  Xiang Y.-T.
Favorite |  | TC[WOS]:0 TC[Scopus]:12 | Submit date：2018/12/18
Adjunctive Treatment  Cognitive Function  Depression  Huperzine a  Meta-analysis  
Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue Journal article
Journal of Molecular Neuroscience, 2015,Volume: 55,Issue: 4,Page: 1014
Authors:  Shengquan Hu;  Rui Wang;  Wei Cui;  Zaijun Zhang;  Shinghung Mak;  Daping Xu;  Chunglit Choi;  Karl Wahkeung Tsim;  Paul R. Carlier;  Mingyuen Lee;  Yifan Han
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date：2018/10/30
Alzheimer’s Disease  Aβ Fibrils  Bis(12)-hupyridone  Cell Viability  Memory Impairment  Thioflavin t  
Huperzine a alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice Journal article
Journal of Neuroscience Research, 2012,Volume: 90,Issue: 2,Page: 508-517
Authors:  Wang Y.;  Tang X.C.;  Zhang H.Y.
Favorite |  | TC[WOS]:44 TC[Scopus]:46 | Submit date：2019/01/16
β-amyloid  Adam10  Alzheimer's disease  Bace1  Huperzine a  
[+]-Huperzine a protects against soman toxicity in guinea pigs Journal article
Neurochemical Research, 2011,Volume: 36,Issue: 12,Page: 2381-2390
Authors:  Wang Y.;  Wei Y.;  Oguntayo S.;  Jensen N.;  Doctor B.P.;  Nambiar M.P.
Favorite |  | TC[WOS]:28 TC[Scopus]:21 | Submit date：2019/01/16
Acetylcholinesterase  Chemical warfare  Huperzine A  Neuroprotection  Seizure  
Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR Journal article
BRAIN RESEARCH, 2011,Volume: 1401,Issue: 15,Page: 10-17
Authors:  Cui, Wei;  Cui, Guo-Zhen;  Li, Wenming;  Zhang, Zaijun;  Hu, Shengquan;  Mak, Shinghung;  Zhang, Huan;  Carlier, Paul R.;  Choi, Chung-lit;  Wong, Yi-Tao;  Lee, Simon Ming-Yuen;  Han, Yifan
Favorite |  | TC[WOS]:22 TC[Scopus]:23 | Submit date：2018/11/01
Bis(12)-hupyridone  Huperzine a  Neural Stem Cell  Neurodegenerative Disorder  Differentiation  Alpha 7nachr  
The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2008,Volume: 46,Issue: 1,Page: 75
Authors:  Yu H.;  Li W.-M.;  Kan K.K.W.;  Ho J.M.K.;  Carlier P.R.;  Pang Y.-P.;  Gu Z.-M.;  Zhong Z.;  Chan K.;  Wang Y.-T.;  Han Y.-F.
Favorite |  | TC[WOS]:34 TC[Scopus]:43 | Submit date：2018/10/30
Ache Inhibition  Bis(12)-hupyridone  Bis(7)-tacrine  Dimer  Ionization Constant  Lipophilicity  Solubility