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Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
The emerging role of KDM5A in human cancer Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Yang,Guan Jun;  Zhu,Ming Hui;  Lu,Xin Jiang;  Liu,Yan Jun;  Lu,Jian Fei;  Leung,Chung Hang;  Ma,Dik Lung;  Chen,Jiong
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/01
Cancer  Drug Resistance  Histone Methylation  Jumonji c Domain  Kdm5a  Targeted Therapy  
Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors:  Wu,Ke Jia;  Ho,Shih Hsin;  Wu,Chun;  Wang,Hui Min D.;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Drug Discovery  Malignant Melanoma  Pan-raf  S100b-p53 Interaction  Synergistic  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Ifn-γ  Licochalcone a  Natural Products  Pd-l1  Protein Synthesis Inhibitor  Ros  
Elevated NSD3 histone methylation activity drives squamous cell lung cancer Journal article
Nature, 2021
Authors:  Yuan,Gang;  Flores,Natasha M.;  Hausmann,Simone;  Lofgren,Shane M.;  Kharchenko,Vladlena;  Angulo-Ibanez,Maria;  Sengupta,Deepanwita;  Lu,Xiaoyin;  Czaban,Iwona;  Azhibek,Dulat;  Vicent,Silvestre;  Fischle,Wolfgang;  Jaremko,Mariusz;  Fang,Bingliang;  Wistuba,Ignacio I.;  Chua,Katrin F.;  Roth,Jack A.;  Minna,John D.;  Shao,Ning Yi;  Jaremko,Łukasz;  Mazur,Pawel K.;  Gozani,Or
Favorite |  | TC[WOS]:12 TC[Scopus]:10 | Submit date:2021/03/04
Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2020,Volume: 6,Issue: 1,Page: 166-174
Authors:  Wu,Ke Jia;  Wu,Chun;  Chen,Feng;  Cheng,Sha Sha;  Ma,Dik Lung;  Leung,Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/03/01
High-throughput Screening  Iridium-based Ph Probe  Lysosomotropic Compounds  Mitoxantrone  Time-resolved Emission Spectroscopy  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Lyu,Junfang;  Yang,Eun Ju;  Zhang,Baoyuan;  Wu,Changjie;  Pardeshi,Lakhansing;  Shi,Changxiang;  Mou,Pui Kei;  Liu,Yifan;  Tan,Kaeling;  Shim,Joong Sup
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/04
Anti-proliferative cassane-type diterpenoids from the seeds of Caesalpinia minax Journal article
Natural Product Research, 2020
Authors:  Xu,Yunshao;  Shi,Wei;  Feng,Lu;  Cao,Jun;  Feng,Zheling;  Zhang,Qingwen;  Lu,Jinjian;  Ye,Yang;  Lin,Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Caesalpinia Minax  Cassane Diterpenoids  Cytotoxic Activity  Fabaceae