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Natural Dietary Compound Xanthohumol Regulates the Gut Microbiota and Its Metabolic Profile in a Mouse Model of Alzheimer’s Disease Journal article
Molecules, 2022,Volume: 27,Issue: 4
Authors:  Liu, Wei;  He, Kaiwu;  Wu, Desheng;  Zhou, Li;  Li, Guowei;  Lin, Zequn;  Yang, Xifei;  Liu, Jianjun;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/04
16s Rdna Sequencing  Alzheimer’s Disease  Gut Microbiota  Microbial Diversity  Xanthohumol  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Other
2022-01-01
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Aging  Alzheimer’s disease  autophagy  machine learning  mitophagy  
The role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer’s disease Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 3,Page: 983-994
Authors:  Shen, Shengnan;  Liao, Qiwen;  Wong, Yin Kwan;  Chen, Xiao;  Yang, Chuanbin;  Xu, Chengchao;  Sun, Jichao;  Wang, Jigang
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Alzheimer’s disease  Anti-inflammatory  Insulin resistance  Melatonin  Mitochondria  Type 2 diabetes  
Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation Journal article
eLife, 2021,Volume: 10
Authors:  Lei, Ienglam;  Tian, Shuo;  Gao, Wenbin;  Liu, Liu;  Guo, Yijing;  Tang, Paul C.;  Chen, Y. Eugene;  Wang, Zhong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
An old weapon with a new function: PIWI-interacting RNAs in neurodegenerative diseases Journal article
Translational Neurodegeneration, 2021,Volume: 10,Issue: 1
Authors:  Huang, Xiaobing;  Wong, Garry
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2021/12/09
H3k9me3  Neurodegenerative Disease  Pirna  Pirna Biogenesis  Transposable Element  
A combined network pharmacology and molecular biology approach to investigate the active ingredients and potential mechanisms of mulberry (Morus alba L.) leaf on obesity Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Li, Ruilin;  Wang, Chunli;  Chen, Yue;  Li, Nannan;  Wang, Qirou;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Hypolipidemic  Mulberry Leaf  Network Pharmacology  Obesity  Pi3k/akt/bcl-xl Signaling Pathways  
SiO2 stimulates macrophage stress to induce the transformation of lung fibroblasts into myofibroblasts and its relationship with the sphingomyelin metabolic pathway Journal article
Journal of Applied Toxicology, 2021,Volume: 41,Issue: 10,Page: 1584-1597
Authors:  Liu, Jing;  Guan, Lan;  Wang, Erjin;  Schuchman, Edward H.;  He, Xingxuan;  Zeng, Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Fibrosis  Hfl-1 Cells  Rac  Silica  Sphingomyelin Signaling Pathway  Thp-1 Cells  
Natural constituents from food sources as therapeutic agents for obesity and metabolic diseases targeting adipose tissue inflammation Journal article
Critical Reviews in Food Science and Nutrition, 2021,Volume: 61,Issue: 12,Page: 1947-1965
Authors:  Li,Dan;  Zhang,Tian;  Lu,Jinjian;  Peng,Cheng;  Lin,Ligen
Favorite |  | TC[WOS]:16 TC[Scopus]:9 | Submit date:2021/03/01
Adipocytes  Adipose Tissue Inflammation  Crosstalk  Dietary Bioactive Nutrients  Macrophages  Metabolic Disease  
β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats Journal article
International Immunopharmacology, 2021,Volume: 98
Authors:  Luo, Huijuan;  Xu, Nan;  Wu, Jiazhen;  Gan, Yuxuan;  Chen, Liping;  Guan, Fengkun;  Li, Mengyao;  Li, Yucui;  Chen, Jiannan;  Su, Ziren;  Liu, Yuhong
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Histanoxia  Non-alcoholic Steatohepatitis  Oxidative Stress  Soluble Cd36  Β-patchoulene  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Biochemical Pharmacology, 2021,Volume: 190
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/12/08
Bacterial Β-glucuronidases  Drug Metabolism  Efficacy/toxicity  Inhibition