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Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylation Journal article
Oncogene, 2021,Volume: 40,Issue: 1,Page: 97-111
Authors:  Zhang,Qingyu;  Zhou,Wei;  Yu,Shan;  Ju,Yaojun;  To,Sally Kit Yan;  Wong,Alice Sze Tsai;  Jiao,Yufei;  Poon,Terence Chuen Wai;  Tam,Kin Yip;  Lee,Leo Tsz On
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Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
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Aib1  Ecm  Hedgehog  Mafb  Pdac  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
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Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Oxygen-Evolving Manganese Ferrite Nanovesicles for Hypoxia-Responsive Drug Delivery and Enhanced Cancer Chemoimmunotherapy Journal article
Advanced Functional Materials, 2021
Authors:  Yang,Kuikun;  Yu,Guocan;  Tian,Rui;  Zhou,Zijian;  Deng,Hongzhang;  Li,Ling;  Yang,Zhen;  Zhang,Guofeng;  Liu,Dahai;  Wei,Jianwen;  Yue,Ludan;  Wang,Ruibing;  Chen,Xiaoyuan
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Chemoimmunotherapy  Drug Delivery  Hypoxia-responsive  Self-assembly  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
BRD4  Bromodomain domain  Cell metastasis and invasion  Histone acetylation  Melanoma  Protein–protein interaction  Virtual screening  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
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The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development Journal article
Medicinal Research Reviews, 2020,Volume: 40,Issue: 6,Page: 2089-2113
Authors:  Farhan,Mohd;  Silva,Marta;  Li,Shuai;  Yan,Fengxia;  Fang,Jiankang;  Peng,Tangming;  Hu,Jim;  Tsao,Ming Sound;  Little,Peter;  Zheng,Wenhua
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autophagy  cancer  FOXO proteins  metastasis  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
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8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis Journal article
Cells, 2020,Volume: 9,Issue: 7
Authors:  Farhan,Mohd;  Silva,Marta;  Xingan,Xing;  Huang,Yu;  Zheng,Wenhua
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angiogenesis  cancer  cancer metabolism  FOXOs  
Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma Journal article
Oncogene, 2020,Volume: 39,Issue: 20,Page: 4061-4076
Authors:  Yang,Xintao;  Hu,Feng;  Liu,Jessica Aijia;  Yu,Shan;  Cheung,May Pui Lai;  Liu,Xuelai;  Ng,Irene Oi Lin;  Guan,Xin Yuan;  Wong,Kelvin K.W.;  Sharma,Rakesh;  Lung,Hong Lok;  Jiao,Yufei;  Lee,Leo Tsz On;  Cheung,Martin
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