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Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways Journal article
Biochemical Pharmacology, 2022,Volume: 197
Authors:  Tu, Yanbei;  Tan, Lihua;  Lu, Tao;  Wang, Kai;  Wang, Haiyong;  Han, Bing;  Zhao, Yuxin;  Chen, Hanbin;  Li, Yanfang;  Chen, Haixia;  Chen, Meiwan;  He, Chengwei
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Glycine Tabacina  Glytabastan b  Inflammation  Network Pharmacology  Osteoclast  Rheumatoid Arthritis  
Rapid Screening of Lipase Inhibitors from Ophiopogonis Radix Using High-Performance Thin Layer Chromatography by Two Step Gradient Elution Combined with Bioautographic Method Journal article
Molecules, 2022,Volume: 27,Issue: 4
Authors:  Hua, Xue;  Hong, Hui Jie;  Zhang, Dai Yan;  Liu, Qiao;  Leong, Fong;  Yang, Qi;  Hu, Yuan Jia;  Chen, Xiao Jia
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Bioautography  High-performance Thin Layer Chromatography  Lipase Inhibitors  Ophiopogonis Radix  Two Step Gradient Elution  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
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3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
Methylaervine as Potential Lead Compound Against Cervical Carcinoma: Pharmacologic Mechanism Prediction based on Network Pharmacology Journal article
Current Computer-Aided Drug Design, 2022,Volume: 18,Issue: 1,Page: 73-80
Authors:  Dan, Wenjia;  Xu, Yujie;  Gu, Hongling;  Gao, Jixiang;  Dai, Jiangkun
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ADME study  Antitumor activity  Docking  Methylaervine  Network pharmacology  Synthesis  
Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking Journal article
Medicine (United States), 2021,Volume: 100,Issue: 51
Authors:  Li, Jialin;  Huang, Zhihong;  Lu, Shan;  Luo, Hua;  Tan, Yingying;  Ye, Peizhi;  Liu, Xinkui;  Wu, Zhishan;  Wu, Chao;  Stalin, Antony;  Wang, Haojia;  Liu, Yingying;  Shen, Liangliang;  Fan, Xiaotian;  Zhang, Bei;  Yi, Jianping;  Yao, Lu;  Xu, Yi;  Wu, Jiarui;  Duan, Xianchun
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Coronavirus Disease 2019  Molecular Docking  Molecular Mechanism  Network Pharmacology  Suhexiang Pill  
Immobilized Kallikrein Microreactor Based on Capillary Electrophoresis for Online Enzyme Kinetics Analysis and Inhibitor Screening Journal article
Chromatographia, 2021,Volume: 84,Issue: 12,Page: 1141-1150
Authors:  Chen, Guo Ying;  Zhang, Hao;  Zhang, Chun Yan;  Wang, Yuan;  Zhao, Cong Peng;  Chen, Hua;  Yang, Feng Qing;  Hu, Yuan Jia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Capillary Electrophoresis  Enzyme Assay  Immobilized Enzyme Microreactor  Kallikrein  Molecular Docking  
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Liu, Jingxin;  Zhang, Tian;  Zhu, Jianzhong;  Ruan, Shuangchen;  Li, Rongsong;  Guo, Bing;  Lin, Ligen
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Hepatocytes  Honokiol  Lipid Accumulation  Lipolysis  Lipophagy  Sirt3  
Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2 Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Dang, Yuan Ye;  Luo, Hua;  Li, Yong Mei;  Zhou, Yang;  Luo, Xiu;  Lin, Shui Mu;  Liu, Shou Ping;  Lee, Simon Ming Yuen;  Li, Chu Wen;  Dai, Xiao Yan
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Arsenic  Autophagy  Carcinogenesis  Curcumin  Gsk-3β/β-trcp  Nrf2  Ros  
Screening of potential thrombin and factor xa inhibitors from the danshen–chuanxiong herbal pair through a spectrum–effect relationship analysis Journal article
Molecules, 2021,Volume: 26,Issue: 23
Authors:  Wang, Xu;  Zhang, Dai Yan;  Yin, Shi Jun;  Jiang, Hui;  Lu, Min;  Yang, Feng Qing;  Hu, Yuan Jia
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Danshen–chuanxiong Herbal Pair  Factor Xa Inhibitors  Spectrum– Effect Relationship Analysis  Thrombin Inhibitors  
LigTMap: ligand and structure-based target identification and activity prediction for small molecular compounds Journal article
Journal of Cheminformatics, 2021,Volume: 13,Issue: 1
Authors:  Shaikh, Faraz;  Tai, Hio Kuan;  Desai, Nirali;  Siu, Shirley W.I.
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/09
Binding Affinity Prediction  Binding Interaction Fingerprint  Drug Repurposing  Fingerprint Similarity  Inverse Docking  Psovina  Random Forest  Target Prediction