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Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways
Journal article
Biochemical Pharmacology, 2022,Volume: 197
Authors:
Tu, Yanbei
;
Tan, Lihua
;
Lu, Tao
;
Wang, Kai
;
Wang, Haiyong
;
Han, Bing
;
Zhao, Yuxin
;
Chen, Hanbin
;
Li, Yanfang
;
Chen, Haixia
;
Chen, Meiwan
;
He, Chengwei
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TC[WOS]:
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TC[Scopus]:
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Submit date:2022/03/28
Glycine Tabacina
Glytabastan b
Inflammation
Network Pharmacology
Osteoclast
Rheumatoid Arthritis
Rapid Screening of Lipase Inhibitors from Ophiopogonis Radix Using High-Performance Thin Layer Chromatography by Two Step Gradient Elution Combined with Bioautographic Method
Journal article
Molecules, 2022,Volume: 27,Issue: 4
Authors:
Hua, Xue
;
Hong, Hui Jie
;
Zhang, Dai Yan
;
Liu, Qiao
;
Leong, Fong
;
Yang, Qi
;
Hu, Yuan Jia
;
Chen, Xiao Jia
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Submit date:2022/03/04
Bioautography
High-performance Thin Layer Chromatography
Lipase Inhibitors
Ophiopogonis Radix
Two Step Gradient Elution
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition
Journal article
Phytomedicine, 2022,Volume: 96
Authors:
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Senapati, Sanjib
;
Malampati, Sandeep
;
Zhu, Zhou
;
Su, Cheng Fu
;
Liu, Jia
;
Guan, Xin Jie
;
Tong, Benjamin Chun Kit
;
Cheung, King Ho
;
Tan, Jie Qiong
;
Lu, Jia Hong
;
Durairajan, Siva Sundara Kumar
;
Song, Ju Xian
;
Li, Min
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TC[WOS]:
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TC[Scopus]:
3
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Submit date:2022/03/04
3xtg-ad Mice
Alzheimer's Disease
Hdac6
P301s-tau Mice
Phospho-tau
Protopine
Methylaervine as Potential Lead Compound Against Cervical Carcinoma: Pharmacologic Mechanism Prediction based on Network Pharmacology
Journal article
Current Computer-Aided Drug Design, 2022,Volume: 18,Issue: 1,Page: 73-80
Authors:
Dan, Wenjia
;
Xu, Yujie
;
Gu, Hongling
;
Gao, Jixiang
;
Dai, Jiangkun
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/03/28
ADME study
Antitumor activity
Docking
Methylaervine
Network pharmacology
Synthesis
Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking
Journal article
Medicine (United States), 2021,Volume: 100,Issue: 51
Authors:
Li, Jialin
;
Huang, Zhihong
;
Lu, Shan
;
Luo, Hua
;
Tan, Yingying
;
Ye, Peizhi
;
Liu, Xinkui
;
Wu, Zhishan
;
Wu, Chao
;
Stalin, Antony
;
Wang, Haojia
;
Liu, Yingying
;
Shen, Liangliang
;
Fan, Xiaotian
;
Zhang, Bei
;
Yi, Jianping
;
Yao, Lu
;
Xu, Yi
;
Wu, Jiarui
;
Duan, Xianchun
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TC[WOS]:
0
TC[Scopus]:
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Submit date:2022/01/14
Coronavirus Disease 2019
Molecular Docking
Molecular Mechanism
Network Pharmacology
Suhexiang Pill
Immobilized Kallikrein Microreactor Based on Capillary Electrophoresis for Online Enzyme Kinetics Analysis and Inhibitor Screening
Journal article
Chromatographia, 2021,Volume: 84,Issue: 12,Page: 1141-1150
Authors:
Chen, Guo Ying
;
Zhang, Hao
;
Zhang, Chun Yan
;
Wang, Yuan
;
Zhao, Cong Peng
;
Chen, Hua
;
Yang, Feng Qing
;
Hu, Yuan Jia
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TC[WOS]:
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TC[Scopus]:
0
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Submit date:2021/12/08
Capillary Electrophoresis
Enzyme Assay
Immobilized Enzyme Microreactor
Kallikrein
Molecular Docking
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Liu, Jingxin
;
Zhang, Tian
;
Zhu, Jianzhong
;
Ruan, Shuangchen
;
Li, Rongsong
;
Guo, Bing
;
Lin, Ligen
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2021/12/08
Hepatocytes
Honokiol
Lipid Accumulation
Lipolysis
Lipophagy
Sirt3
Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Dang, Yuan Ye
;
Luo, Hua
;
Li, Yong Mei
;
Zhou, Yang
;
Luo, Xiu
;
Lin, Shui Mu
;
Liu, Shou Ping
;
Lee, Simon Ming Yuen
;
Li, Chu Wen
;
Dai, Xiao Yan
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TC[WOS]:
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TC[Scopus]:
1
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Submit date:2021/12/08
Arsenic
Autophagy
Carcinogenesis
Curcumin
Gsk-3β/β-trcp
Nrf2
Ros
Screening of potential thrombin and factor xa inhibitors from the danshen–chuanxiong herbal pair through a spectrum–effect relationship analysis
Journal article
Molecules, 2021,Volume: 26,Issue: 23
Authors:
Wang, Xu
;
Zhang, Dai Yan
;
Yin, Shi Jun
;
Jiang, Hui
;
Lu, Min
;
Yang, Feng Qing
;
Hu, Yuan Jia
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2022/01/14
Danshen–chuanxiong Herbal Pair
Factor Xa Inhibitors
Spectrum– Effect Relationship Analysis
Thrombin Inhibitors
LigTMap: ligand and structure-based target identification and activity prediction for small molecular compounds
Journal article
Journal of Cheminformatics, 2021,Volume: 13,Issue: 1
Authors:
Shaikh, Faraz
;
Tai, Hio Kuan
;
Desai, Nirali
;
Siu, Shirley W.I.
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2021/12/09
Binding Affinity Prediction
Binding Interaction Fingerprint
Drug Repurposing
Fingerprint Similarity
Inverse Docking
Psovina
Random Forest
Target Prediction