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Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes Journal article
European Journal of Medicinal Chemistry, 2022,Volume: 237
Authors:  Zhao, Jiannan;  Li, Yongling;  Ma, Jing;  Liu, Jingting;  Xiao, Ruoxuan;  Wang, Linlin;  Li, Peng;  He, Yinyan;  Qian, Feng;  Zhang, Ao;  Sun, Zhen Liang;  Ding, Chunyong
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/13
Fluorescence Imaging  Inflammasome  Inhibitor  Nlrp3  Sulfonylurea  
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice Journal article
Chinese Medicine (United Kingdom), 2022,Volume: 17,Issue: 1
Authors:  Zou, Jian;  Yan, Chunyan;  Wan, Jian Bo
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Lipid Synthesis  Nafld  Nf-κb  Nlrp3 Inflammasome  Red Yeast Rice  
Rhein regulates redox-mediated activation of NLRP3 inflammasomes in intestinal inflammation through macrophage-activated crosstalk Journal article
British Journal of Pharmacology, 2021,Volume: 179,Issue: 9,Page: 1978-1997
Authors:  Zhou, Yangyang;  Gao, Caifang;  Vong, Chi Teng;  Tao, Hongxun;  Li, Hongyi;  Wang, Shengpeng;  Wang, Yitao
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Anthraquinone  Colonic Inflammation  Macrophage Polarization  Nadph Oxidase  Nlrp3 Inflammasome  Nrf2  
Guaianolides from Artemisia codonocephala suppress interleukine-1β secretion in macrophages Journal article
Phytochemistry, 2021,Volume: 192
Authors:  Wang, Qiaoqiao;  Zhang, Tian;  Ke, Chang Qiang;  Tang, Chunping;  Yao, Sheng;  Lin, Ligen;  Ye, Yang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Anti-inflammation  Artemisia Codonocephala  Asteraceae  Guaianolides  Il-1β  Nlrp3  
β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats Journal article
International Immunopharmacology, 2021,Volume: 98
Authors:  Luo, Huijuan;  Xu, Nan;  Wu, Jiazhen;  Gan, Yuxuan;  Chen, Liping;  Guan, Fengkun;  Li, Mengyao;  Li, Yucui;  Chen, Jiannan;  Su, Ziren;  Liu, Yuhong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Histanoxia  Non-alcoholic Steatohepatitis  Oxidative Stress  Soluble Cd36  Β-patchoulene  
Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease Journal article
Biomedicine and Pharmacotherapy, 2021,Volume: 138
Authors:  Chen, Qiu Ling;  Yin, Hao Ran;  He, Qing Yu;  Wang, Ying
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/12/08
Inflammatory Bowel Disease  Nlrp3  Small Molecule Inhibitor  Targeted Therapy  
Specific NLRP3 inflammasome inhibitors: promising therapeutic agents for inflammatory diseases Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 6,Page: 1394-1408
Authors:  Vong, Chi Teng;  Tseng, Hisa Hui Ling;  Yao, Peifen;  Yu, Hua;  Wang, Shengpeng;  Zhong, Zhangfeng;  Wang, Yitao
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/09/13
Biscaesalmins A and B from Caesalpinia minax, highly oxidized dimeric cassane diterpenoids as interleukin-1β inhibitors Journal article
Chinese Chemical Letters, 2021,Volume: 32,Issue: 4,Page: 1475-1479
Authors:  Xu,Yunshao;  Zhang,Tian;  Feng,Lu;  Feng,Zheling;  Zhang,Qingwen;  Ye,Yang;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Caesalpinia Minax  Dimeric Cassane Diterpenoids  Il-1β  Nlrp3  Td-dft  
Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury Journal article
Pharmacological Research, 2021,Volume: 164
Authors:  Zou,Jian;  Wang,Sheng Peng;  Wang,Yi Tao;  Wan,Jian Bo
Favorite |  | TC[WOS]:9 TC[Scopus]:7 | Submit date:2021/03/02
Acute Liver Failure  Chemical-induced Liver Injury  Inflammation  Natural Products  Nlrp3 Inflammasome  
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis Journal article
Acta Pharmacologica Sinica, 2021
Authors:  Chen, Cheng;  Ren, Yong mei;  Zhu, Jian zhong;  Chen, Jia li;  Feng, Zhe ling;  Zhang, Tian;  Ye, Yang;  Lin, Li gen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/13
adipose tissue inflammation  Ainsliadimer C  dexamethasone  EX-527  interleukin-1β  macrophages  metabolic disorders  NLRP3 inflammasome  obesity  Sirtuin 1