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A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy Journal article
Trends in Cell Biology, 2021
Authors:  Lu,Guang;  Wang,Liming;  Zhou,Jing;  Liu,Wei;  Shen,Han Ming
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Autophagy  Cancer  Cullin-ring E3 Ligases  Mtorc1  Neddylation  Ubiquitination  
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:40 TC[Scopus]:40 | Submit date:2018/10/30
Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2017,Volume: 313,Issue: 1,Page: L104-L114
Authors:  Zhu, Ziyan;  Sun, Lei;  Hao, Rui;  Jiang, Hongchao;  Qian, Feng;  Ye, Richard D.
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2018/10/30
Cullin-5  macrophage  Nedd8  acute lung injury  
Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening Journal article
Biochimie, 2012,Volume: 94,Issue: 11,Page: 2457-2460
Authors:  Zhong H.-J.;  Pui-Yan Ma V.;  Cheng Z.;  Shiu-Hin Chan D.;  He H.-Z.;  Leung K.-H.;  Ma D.-L.;  Leung C.-H.
Favorite |  | TC[WOS]:52 TC[Scopus]:52 | Submit date:2018/10/30
Drug Discovery  Natural Product  Nedd8-activating Enzyme  Ubiquitin-like Protein  Virtual Screening  
A Metal-Based Inhibitor of NEDD8-Activating Enzyme Journal article
PLoS ONE, 2012,Volume: 7,Issue: 11
Authors:  Hai-Jing Zhong;  Hui Yang;  Chung-Hang Leung;  Leung C.-H.;  Hui-Min Wang;  DikLung Ma
Favorite |  | TC[WOS]:32 TC[Scopus]:37 | Submit date:2018/10/30