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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
3,4′,5-Trimethoxy-trans-stilbene Alleviates Endothelial Dysfunction in Diabetic and Obese Mice via Activation of the AMPK/SIRT1/eNOS Pathway Journal article
Antioxidants, 2022,Volume: 11,Issue: 7,Page: 1286
Authors:  Tan, Yi;  Zhou, Chunxiu;  Xu, Baojun;  Wang, Yitao;  Cheang, Wai San
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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
Anti-Parkinsonian Therapy: Strategies for Crossing the Blood–Brain Barrier and Nano-Biological Effects of Nanomaterials Journal article
Nano-Micro Letters, 2022,Volume: 14,Issue: 1
Authors:  Cheng, Guowang;  Liu, Yujing;  Ma, Rui;  Cheng, Guopan;  Guan, Yucheng;  Chen, Xiaojia;  Wu, Zhenfeng;  Chen, Tongkai
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Biomimetic Drug Delivery  Blood–brain Barrier  Nano-biological Effects  Nasal Delivery  Parkinson’s Disease  
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:  Deng, Zhiqiang;  Dong, Yu;  Zhou, Xiaoting;  Lu, Jia Hong;  Yue, Zhenyu
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Alzheimer's disease  Autophagy  Autophagy modulators  Genetic modulation  LC3-associated phagocytosis  Microglial autophagy  Neuroinflammation  Neuronal autophagy  
Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1987-1999
Authors:  He, Xueqin;  Wang, Xiaorong;  Yang, Lianyi;  Yang, Zhihang;  Yu, Wenqi;  Wang, Yazhen;  Liu, Rui;  Chen, Meiwan;  Gao, Huile
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Alzheimer's disease  Anti-neuroinflammation  Blood‒brain barrier transcytosis  Drug combination  Nano drug delivery system  Neuroprotection  Receptor for advanced glycation end products  ROS-responsive  
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 7
Authors:  Guan, Xinjie;  Iyaswamy, Ashok;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Su, Chengfu;  Zhu, Zhou;  Liu, Jia;  Kan, Yuxuan;  Cheung, King Ho;  Lu, Jiahong;  Tan, Jieqiong;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/04
Aggrephagy  Alzheimer’s Disease  Lipophagy  Lysophagy  Mitophagy  Nucleophagy  Pexophagy  Reticulophagy  Ribophagy  Selective Autophagy  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/04/06
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
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Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Dysregulation of Human Somatic piRNA Expression in Parkinson’s Disease Subtypes and Stages Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 5
Authors:  Zhang, Tianjiao;  Wong, Garry
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2022/03/28
Biomarker  Parkinson’s Disease  Pirna  Somatic Pirna  Spls-da