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A multi-omics analysis for prediction of neurocognitive disorders risk among the elderly in Macao. Clinical and Translational Medicine Journal article
Clinical and Translational Medicine, 2022,Volume: 12,Page: e909
Authors:  Yan Han;  Xingping Quan;  Yaochen Chuang;  Qiaoxing Liang;  Yang Li;  Zhen Yuan;  Ying Bian;  Lai Wei;  JiWang;  Yonghua Zhao
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Exosomes  Gut Microbiota  Multi-omics  Neurocognitive Disorders  
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:  Deng, Zhiqiang;  Dong, Yu;  Zhou, Xiaoting;  Lu, Jia Hong;  Yue, Zhenyu
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date：2022/05/13
Alzheimer's disease  Autophagy  Autophagy modulators  Genetic modulation  LC3-associated phagocytosis  Microglial autophagy  Neuroinflammation  Neuronal autophagy  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
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Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
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Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
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3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
Icariin ameliorate Alzheimer's disease by influencing SIRT1 and inhibiting Aβ cascade pathogenesis Journal article
Journal of Chemical Neuroanatomy, 2021,Volume: 117
Authors:  Chuang, Yaochen;  Van, Iatkio;  Zhao, Yonghua;  Xu, Youhua
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Alzheimer's Disease  Amyloid-β Cascade  Icariin  Sirtuin1  Traditional Chinese Medicine  
Engineered exosomes: Desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies Journal article
Theranostics, 2021,Volume: 11,Issue: 18,Page: 8926-8944
Authors:  Xu, Meng;  Feng, Tao;  Liu, Bowen;  Qiu, Fen;  Xu, Youhua;  Zhao, Yonghua;  Zheng, Ying
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Administration Routes  Brain Targeting  Cerebrovascular Disease  Engineered Exosomes  Neurological Disorders  Tracking  
Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer’s Disease Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Iyaswamy,A.;  Krishnamoorthi,S. K.;  Liu,Y. W.;  Song,J. X.;  Kammala,A. K.;  Sreenivasmurthy,S. G.;  Malampati,S.;  Tong,B. C.K.;  Selvarasu,K.;  Cheung,K. H.;  Lu,J. H.;  Tan,J. Q.;  Huang,C. Y.;  Durairajan,S. S.K.;  Li,M.
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Alzheimer’s Disease  Chinese Medicine  Connectivity Map  Microarray  Neurofibrillary Tangles  P301s Tau Mice  Yuan-hu Zhi Tong  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
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App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite |  | TC[WOS]:17 TC[Scopus]:15 | Submit date：2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen