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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth Journal article
Pharmacological Research, 2022,Volume: 179
Authors:  Huang, Bin;  Hao, Meng;  Li, Chuwen;  Luo, Kathy Qian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Acetyltanshinone IIA  Afatinib (PubChem CID: 10184653)  Aurora kinase A  Drug-resistant lung cancer  EGFR  Erlotinib (PubChem CID: 176870)  LY294002 (PubChem CID: 3973)  MLN8237 (PubChem CID: 24771867)  Osimertinib (PubChem CID: 71496458)  P70S6K  PF-4708671 (PubChem CID: 51371303)  Rapamycin (PubChem CID: 5284616)  Tanshinone IIA (PubChem CID: 164676)  
2-Methoxy-6-acetyl-7-methyljuglone (MAM) Activated Necroptosis as A New Therapeutic Avenue for Non-Small Cell Lung Cancer Resistant to EGFR Tyrosine Kinase Inhibitor Osimertinib Project
项目编号: MYRG2020-00053-ICMS, 2022-
Authors:  XPCHEN
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/02/16
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/12/08
Drug Resistance  Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor  Non-small Cell Lung Cancer  Targeted Therapy  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date:2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Remodeling of Tumor Microenvironment by Tumor-Targeting Nanozymes Enhances Immune Activation of CAR T Cells for Combination Therapy Journal article
Small, 2021,Volume: 17,Issue: 43
Authors:  Zhu, Lipeng;  Liu, Jie;  Zhou, Guangyu;  Liu, Tzu Ming;  Dai, Yunlu;  Nie, Guangjun;  Zhao, Qi
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/12/08
B7-h3 Immune Checkpoint  Chimeric Antigen Receptor t Cell  Immunotherapy  Nanozyme  Photothermal-nanocatalytic Effect  
Oxidative stress-mediated AMPK inactivation determines the high susceptibility of LKB1-mutant NSCLC cells to glucose starvation Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 128-139
Authors:  Ren, Yi;  Chen, Jiaqing;  Chen, Peishi;  Hao, Qi;  Cheong, Leng Kuan;  Tang, Mingzhu;  Hong, Lian Lian;  Hu, Xuan Yu;  Celestial T Yap,;  Bay, Boon Huat;  Ling, Zhi Qiang;  Shen, Han Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/11/30
Amp-activated Protein Kinase  Glucose Starvation  Liver Kinase B1  Non-small Cell Lung Cancer  Reactive Oxygen Species  
Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:17 TC[Scopus]:17 | Submit date:2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
PLGA nanofiber/PDMS microporous composite membrane-sandwiched microchip for drug testing Journal article
Micromachines, 2020,Volume: 11,Issue: 12,Page: 1-13
Authors:  Li, Wei;  Sun, Xindi;  Ji, Bing;  Yang, Xingyuan;  Zhou, Bingpu;  Lu, Zhanjun;  Gao, Xinghua
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/09/17
Composite Membrane  Drug Evaluation  Lung-on-a-chip  Microfluidic Chip  Organ-on-a-chip  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/02
Targeting RNA helicase DHX33 blocks Ras-driven lung tumorigenesis in vivo Journal article
Cancer Science, 2020,Volume: 111,Issue: 10,Page: 3564-3575
Authors:  Wang,Xingshun;  Feng,Weimin;  Peng,Cheng;  Chen,Shiyun;  Ji,Hongbin;  Zhong,Hanbing;  Ge,Wei;  Zhang,Yandong
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/02
Dhx33  Lung Cancer  Oncogene  Ras  Rna Helicase