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Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer’s Disease. Oxidative Medicine and Cellular Longevit Journal article
Oxidative Medicine and Cellular Longevity, 2022,Volume: 2022,Page: 21
Authors:  Qin Li;  Limor Rubin;  Marta Silva;  Shuai Li;  Chao Yang;  Philip Lazarovici;  Zheng WH(鄭文華)
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A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury Journal article
Redox Biology, 2021,Volume: 48
Authors:  Li, Guodong;  Liu, Hao;  Feng, Ruibing;  Kang, Tian Shu;  Wang, Wanhe;  Ko, Chung Nga;  Wong, Chun Yuen;  Ye, Min;  Ma, Dik Lung;  Wan, Jian Bo;  Leung, Chung Hang
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date:2022/05/13
Inhibitor  Iridium(III) complex  Kelch-like ECH-Associated protein 1  Liver injury  Nuclear factor E2-related factor 2  
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2021,Volume: 173,Page: 64-69
Authors:  Yu, Jie;  Zhong, Bingling;  Zhao, Lin;  Hou, Ying;  Wang, Xianzhe;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Nec-1  Nec-1s  Nqo1  Ripk1  
Pinocembrin-7-Methylether Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity via Modulating Nrf2 Induction Through AKT and ERK Pathways Journal article
Neurotoxicity Research, 2021,Volume: 39,Issue: 4,Page: 1323-1337
Authors:  Zou, Zhi Cong;  Fu, Ji Jun;  Dang, Yuan Ye;  Zhang, Qian;  Wang, Xiu Fen;  Chen, Han Bin;  Jia, Xue Jing;  Lee, Simon Ming Yuen;  Li, Chu Wen
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/12/08
6-ohda  Nrf2 Induction  Oxidative Stress  Parkinson’s Disease  Pinocembrin-7-methylether  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/09/17
Cell Death  Danshen  Noptosis  Nqo1  
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2020,Volume: 152,Page: 336-347
Authors:  Yu, Jie;  Zhong, Bingling;  Jin, Long;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Li, Luoxiang;  Liu, Shuqin;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:12 TC[Scopus]:15 | Submit date:2021/09/17
Mam  Glioblastoma  Programmed Necrosis  Nqo1  
Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4/MyD88 signaling pathway Journal article
Chinese Medicine, 2020,Volume: 15,Issue: 1
Authors:  Li, Xin Xing;  Zheng, Xiaoting;  Liu, Zhenjie;  Xu, Qiongming;  Tang, Hongzhen;  Feng, Jianfang;  Yang, Shilin;  Vong, Chi Teng;  Gao, Hongwei;  Wang, Yitao
Favorite |  | TC[WOS]:13 TC[Scopus]:16 | Submit date:2021/09/13
Anti-inflammation  Cryptotanshinone  Nrf2  Pi3k/akt  Tlr4-myd88  
2-甲氧基-6-乙酰基-7-甲基胡桃酮的应用 Patent
专利类型: 发明专利Invention, 专利号: CN110772503A, 申请日期: 2019-10-11,
Authors:  陈修平;  葛伟;  余洁;  钟冰玲
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Nqo1  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
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App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by MAM Conference paper
Collection of 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Sun, W.;  Hou, Y.;  Zhang, Y.Y.;  Li, Z.W.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  necroptosis  glioma