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Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
Favorite |  | TC[WOS]:1 TC[Scopus]:3 | Submit date:2021/03/02
Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cancer metabolism  Cancer proliferation  Dual inhibitor  Lactate dehydrogenase A  Pyruvate dehydrogenase kinase  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
Favorite |  | TC[WOS]:6 TC[Scopus]:8 | Submit date:2021/03/04
3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells  
Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway Journal article
Stem Cell Research and Therapy, 2019,Volume: 10,Issue: 1
Authors:  Fang,Jiankang;  Zhao,Xia;  Li,Shuai;  Xing,Xingan;  Wang,Haitao;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:14 TC[Scopus]:15 | Submit date:2021/03/04
Apoptosis  Artemisinin  Bone marrow mesenchymal stem cells  CREB  Erk1/2  p90rsk  Phosphorylation  Protection  Raf  ROS  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite |  | TC[WOS]:16 TC[Scopus]:16 | Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite |  | TC[WOS]:5 TC[Scopus]:9 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Artemisinin attenuated hydrogen peroxide (H2o2)-induced oxidative injury in SH-SY5Y and hippocampal neurons via the activation of AMPK pathway Journal article
International Journal of Molecular Sciences, 2019,Volume: 20,Issue: 11
Authors:  Zhao,Xia;  Fang,Jiankang;  Li,Shuai;  Gaur,Uma;  Xing,Xingan;  Wang,Huan;  Zheng,Wenhua
Favorite |  | TC[WOS]:12 TC[Scopus]:18 | Submit date:2021/03/04
AMPK pathway  Artemisinin  H2O2  Hippocampal neurons  SH-SY5Y cells  
Dual ph and oxygen luminescent nanosensors for extracellular metabolism monitoring Conference paper
Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, Seattle, 3 April 2019 - 6 April 2019
Authors:  Yang,Cheng;  Pan,Tingting;  Chen,Meiwan;  Tian,Yanqing
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Re-analysis of the coral Acropora digitifera transcriptome reveals a complex lncRNAs-mRNAs interaction network implicated in Symbiodinium infection Journal article
BMC Genomics, 2019,Volume: 20,Issue: 1
Authors:  Huang C.;  Leng D.;  Sun S.;  Zhang X.D.
Adobe PDF | Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/03
Acropora Digitifera  Alternative Splicing  Deep Rna-sequencing  Long Non-coding Rnas  Symbiodinium  Transcriptome  
Artemether Activation of AMPK/GSK3 β (ser9)/Nrf2 Signaling Confers Neuroprotection towards β- Amyloid-Induced Neurotoxicity in 3xTg Alzheimer's Mouse Model Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Li,Shuai;  Zhao,Xia;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:15 TC[Scopus]:17 | Submit date:2021/03/04