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Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Acta Pharmacologica Sinica, 2022
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Guan, Xin jie;  Kan, Yu xuan;  Xie, Wen jian;  Zhao, Chen liang;  Cheung, King ho;  Lu, Jia hong;  Tan, Jie qiong;  Zhang, Hong jie;  Song, Ju xian;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
autophagy  corynoxine B  dopaminergic neuron  MPP+  oxindole alkaloid  Parkinson’s disease  PI3P  PIK3C3 complex  
Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:  Lin, Ruohong;  Liu, Linlin;  Silva, Marta;  Fang, Jiankang;  Zhou, Zhiwei;  Wang, Haitao;  Xu, Jiangping;  Li, Tiejun;  Zheng, Wenhua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Akt  Corticosterone  Depression  Hederagenin  Pathway  Pc12 Cells  Pi3k  
Synthesis and evolution of neuroprotective effects of oxymatrine derivatives as anti-Alzheimer’s disease agents Journal article
Chemical Biology and Drug Design, 2021,Volume: 98,Issue: 1,Page: 175-181
Authors:  Dong, Pei Liang;  Li, Zheng Qing;  Teng, Cui li;  Yin, Xin;  Cao, Xian Kai;  Han, Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Alzheimer's Disease  Neuroprotective  Oxymatrine  Oxymatrine Derivatives  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Phytomedicine, 2021,Volume: 87
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan;  Cai, Cui zan;  Tan, Jie qiong;  Su, Huan xing;  Lu, Jia hong
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein  
Amauroderma rugosum Protects PC12 Cells against 6-OHDA-Induced Neurotoxicity through Antioxidant and Antiapoptotic Effects Journal article
Oxidative Medicine and Cellular Longevity, 2021,Volume: 2021
Authors:  Li, Jingjing;  Li, Renkai;  Wu, Xiaoping;  Hoo, Ruby Lai Chong;  Lee, Simon Ming Yuen;  Cheung, Timothy Man Yau;  Ho, Bryan Siu Yin;  Leung, George Pak Heng
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2022/05/13
Botanical drug puerarin promotes neuronal survival and neurite outgrowth against mptp/mpp+-induced toxicity via progesterone receptor signaling Journal article
Oxidative Medicine and Cellular Longevity, 2020,Volume: 2020
Authors:  Zhao,Yingke;  Zhao,Jia;  Zhang,Xiuying;  Cheng,Yuanyuan;  Luo,Dan;  Lee,Simon Ming Yuen;  Lao,Lixing;  Rong,Jianhui
Favorite |  | TC[WOS]:9 TC[Scopus]:8 | Submit date:2021/03/01
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Hu,Wei Hui;  Mak,Shing Hung;  Zheng,Zhong Yu;  Xia,Ying Jie;  Xu,Miranda Li;  Duan,Ran;  Dong,Tina Ting Xia;  Li,Shao Ping;  Zhan,Chang Sen;  Shang,Xiao Hui;  Tsim,Karl Wah Keung
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/01
Acetylcholinesterase  Alzheimer’s Disease  Chinese Medicine  Cognitive Enhancing Effect  Neuroprotective  Shexiang Baoxin Pill  
Foxo3a suppresses neuropeptide w expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 15,Page: 2775-2787
Authors:  Yan,Fengxia;  Wang,Rikang;  Li,Shuai;  Zhao,Xia;  Jiang,Yizhou;  Liu,Linlin;  Fang,Jiankang;  Zhen,Xuechu;  Lazarovici,Philip;  Zheng,Wenhua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
FoxO3a  Glucocorticoids  HPA axis dysfunction  Hypothalamus  Neuropeptide W (NPW)  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen;  Gao,Cheng;  Di,Lijun;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:10 TC[Scopus]:9 | Submit date:2021/03/01
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite |  | TC[WOS]:21 TC[Scopus]:21 | Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells