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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation
Journal article
Phytomedicine, 2022,Volume: 101
Authors:
Chen, Jia Yue
;
Zhu, Qi
;
Cai, Cui Zan
;
Luo, Hai Bin
;
Lu, Jia Hong
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Submit date:2022/05/31
Alpha-synuclein (Α-syn)
Parkinson's Disease
Phosphodiesterase 4 Inhibitor
Protein Kinase a (Pka)
Ubiquitin-proteasome System (Ups)
Automatic Detection Pipeline for Accessing the Motor Severity of Parkinson’s Disease in Finger Tapping and Postural Stability
Journal article
IEEE Access, 2022,Volume: 10,Page: 66961
Authors:
Ning Yang
;
De-Feng Liu
;
Tao Liu
;
Tianyuan Han
;
Pingyue Zhang
;
Xuenan Xu
;
Siyu Lou
;
Huan-guang Liu
;
An-Chao Yang
;
Cheng Dong
;
Mang I Vai
;
Sio Hang Pun
;
Jian-Guo Zhang
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Submit date:2022/08/07
Activity Recognition
Deep Learning
Finger Tapping
Neural Network
Parkinson’s Disease
Pose Estimation
Postural Stability
Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin
Journal article
eFood, 2022,Volume: 3,Issue: e3
Authors:
Ruting ZHONG
;
Mohamed A. Farag
;
Meiwan Che
;
Chengwei He
;
Jianbo Xiao
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Submit date:2022/07/29
Bioactivities
Fisetin
Molecular Mechanism
Pharmacokinetics
Structure–activity Relationship
Using flavonoids as a therapeutic intervention against rheumatoid arthritis: The known and unknown
Journal article
Pharmacological Research - Modern Chinese Medicine, 2022,Volume: 3,Issue: 2022
Authors:
Zhimin Miao
;
Yuxin Zhao
;
Meiwan Chen
;
Chengwei He
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Submit date:2022/07/29
Rheumatoid Arthritis
Flavonoids
Immunoregulation
Gut-joint Axis
Inflammatory Responses
Anti-Parkinsonian Therapy: Strategies for Crossing the Blood–Brain Barrier and Nano-Biological Effects of Nanomaterials
Journal article
Nano-Micro Letters, 2022,Volume: 14,Issue: 1
Authors:
Cheng, Guowang
;
Liu, Yujing
;
Ma, Rui
;
Cheng, Guopan
;
Guan, Yucheng
;
Chen, Xiaojia
;
Wu, Zhenfeng
;
Chen, Tongkai
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TC[WOS]:
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TC[Scopus]:
2
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Submit date:2022/05/13
Biomimetic Drug Delivery
Blood–brain Barrier
Nano-biological Effects
Nasal Delivery
Parkinson’s Disease
Dysregulation of Human Somatic piRNA Expression in Parkinson’s Disease Subtypes and Stages
Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 5
Authors:
Zhang, Tianjiao
;
Wong, Garry
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TC[WOS]:
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Submit date:2022/03/28
Biomarker
Parkinson’s Disease
Pirna
Somatic Pirna
Spls-da
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy
Journal article
Acta Pharmacologica Sinica, 2022
Authors:
Zhu, Zhou
;
Liu, Liang feng
;
Su, Cheng fu
;
Liu, Jia
;
Tong, Benjamin Chun Kit
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Guan, Xin jie
;
Kan, Yu xuan
;
Xie, Wen jian
;
Zhao, Chen liang
;
Cheung, King ho
;
Lu, Jia hong
;
Tan, Jie qiong
;
Zhang, Hong jie
;
Song, Ju xian
;
Li, Min
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2022/05/17
Autophagy
Corynoxine b
Dopaminergic Neuron
Mpp++++
Oxindole Alkaloid
Parkinson’s Disease
Pi3p
Pik3c3 Complex
Establish a Sensor Zebrafish Model and Use It to Study the Roles of Genetic Factors in Promoting Parkinson’s Disease-related Neuronal Cell Death
Project
项目编号: MYRG2020-00121-FHS, 2022-
Authors:
KLUO
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Submit date:2022/02/16
Role of piRNAs in Alzheimer’s and Parkinson’s Disease
Project
项目编号: MYRG2020-00213-FHS, 2022-
Authors:
GARRYGWONG
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Submit date:2022/02/16
Automatic Detection Pipeline for Accessing the Motor Severity of Parkinson's Disease in Finger Tapping and Postural Stability
Journal article
IEEE Access, 2022,Volume: 10,Page: 66961-66973
Authors:
Yang, Ning
;
Liu, De Feng
;
Liu, Tao
;
Han, Tianyuan
;
Zhang, Pingyue
;
Xu, Xuenan
;
Lou, Siyu
;
Liu, Huan Guang
;
Yang, An Chao
;
Dong, Cheng
;
Vai, Mang I.
;
Pun, Sio Hang
;
Zhang, Jian Guo
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TC[WOS]:
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Submit date:2022/08/05
Activity recognition
deep learning
finger tapping
neural network
Parkinsona's disease
pose estimation
postural stability