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Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies Journal article
CNS Neuroscience and Therapeutics, 2021,Volume: 27,Issue: 3,Page: 270-279
Authors:  Zhao,Na;  Yang,Yuan;  Zhang,Ling;  Zhang,Qinge;  Balbuena,Lloyd;  Ungvari,Gabor S.;  Zang,Yu Feng;  Xiang,Yu Tao
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comparative study  meta-analysis  Parkinson's disease  quality of life  
Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu,Jian;  Wang,Liming;  Zhang,Lihuan;  Zheng,Fang;  Wang,Fang;  Leng,Jianhang;  Wang,Keyi;  Héroux,Paul;  Shen,Han Ming;  Wu,Yihua;  Xia,Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review Journal article
Biomedicine and Pharmacotherapy, 2021,Volume: 133
Authors:  Wang,Zi Ying;  Liu,Jia;  Zhu,Zhou;  Su,Cheng Fu;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Iyaswamy,Ashok;  Lu,Jia Hong;  Chen,Gang;  Song,Ju Xian;  Li,Min
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Autophagy  Neurodegenerative disease  Neuroprotection  Traditional Chinese medicine  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong,Sha;  Li,Zhongjun;  Liu,Yao;  Wang,Qun;  Luo,Jingshan;  Chen,Xiaojia;  Xie,Zhongjian;  Zhang,Yuan;  Zhang,Han;  Chen,Tongkai
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Black phosphorus nanosheets  Blood-brain barrier  Brain targeting  Drug delivery  Lactoferrin  
NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 10,Page: 6876-6887
Authors:  Liu,Yao;  Zhu,Daoming;  Luo,Jingshan;  Chen,Xiaojia;  Gao,Liqian;  Liu,Wei;  Chen,Tongkai
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blood-brain barrier  brain drug delivery  gold nanorods  mesoporous silica  neurodegenerative disorders  NIR-II biowindow  
Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bian,Yaqi;  Zhao,Chen;  Lee,Simon Ming Yuen
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anti-depressant effect  anxiolytic effect  neuroprotective effects  saffron  saffron constituents  traditional Chinese medicine  
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther;  Lakso,Merja;  Wong,Garry
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C. Elegans  Lewy Body Dementia  Neurodegeneration  Parkinson's Disease  Tdp-1/tdp-43  Tdp-43  Α-synuclein  
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
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Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han,Chaojun;  Yan,Pengju;  He,Tao;  Cheng,Junjie;  Zheng,Wenhua;  Zheng,Long Tai;  Zhen,Xuechu
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Dopaminergic neuron  Microglia  Neuroinflammation  NF-κB  PHLDA1  TRAF6  Ubiquitination  
Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2020,Volume: 15,Issue: 4,Page: 518-528
Authors:  Xiong,Sha;  Liu,Wei;  Zhou,Yile;  Mo,Yousheng;  Liu,Yao;  Chen,Xiaojia;  Pan,Huafeng;  Yuan,Dongsheng;  Wang,Qi;  Chen,Tongkai
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Anti-Parkinsonian efficacy  Brain permeability  Nanocrystals  Oral absorption  Resveratrol