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Quality of life in Parkinson's disease: A systematic review and meta-analysis of comparative studies Journal article
CNS Neuroscience and Therapeutics, 2021,Volume: 27,Issue: 3,Page: 270-279
Authors:  Zhao，Na;  Yang，Yuan;  Zhang，Ling;  Zhang，Qinge;  Balbuena，Lloyd;  Ungvari，Gabor S.;  Zang，Yu Feng;  Xiang，Yu Tao
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comparative study  meta-analysis  Parkinson's disease  quality of life  
Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity Journal article
Redox Biology, 2021,Volume: 38
Authors:  Xu，Jian;  Wang，Liming;  Zhang，Lihuan;  Zheng，Fang;  Wang，Fang;  Leng，Jianhang;  Wang，Keyi;  Héroux，Paul;  Shen，Han Ming;  Wu，Yihua;  Xia，Dajing
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Cell death  Cytotoxicity  MEHP  Mitochondrial ROS  PINK1-Parkin-mediated mitophagy  
Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review Journal article
Biomedicine and Pharmacotherapy, 2021,Volume: 133
Authors:  Wang，Zi Ying;  Liu，Jia;  Zhu，Zhou;  Su，Cheng Fu;  Sreenivasmurthy，Sravan Gopalkrishnashetty;  Iyaswamy，Ashok;  Lu，Jia Hong;  Chen，Gang;  Song，Ju Xian;  Li，Min
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Autophagy  Neurodegenerative disease  Neuroprotection  Traditional Chinese medicine  
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease Journal article
Biomaterials, 2020,Volume: 260
Authors:  Xiong，Sha;  Li，Zhongjun;  Liu，Yao;  Wang，Qun;  Luo，Jingshan;  Chen，Xiaojia;  Xie，Zhongjian;  Zhang，Yuan;  Zhang，Han;  Chen，Tongkai
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Black phosphorus nanosheets  Blood-brain barrier  Brain targeting  Drug delivery  Lactoferrin  
NIR-II-Activated Yolk-Shell Nanostructures as an Intelligent Platform for Parkinsonian Therapy Journal article
ACS Applied Bio Materials, 2020,Volume: 3,Issue: 10,Page: 6876-6887
Authors:  Liu，Yao;  Zhu，Daoming;  Luo，Jingshan;  Chen，Xiaojia;  Gao，Liqian;  Liu，Wei;  Chen，Tongkai
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blood-brain barrier  brain drug delivery  gold nanorods  mesoporous silica  neurodegenerative disorders  NIR-II biowindow  
Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bian，Yaqi;  Zhao，Chen;  Lee，Simon Ming Yuen
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anti-depressant effect  anxiolytic effect  neuroprotective effects  saffron  saffron constituents  traditional Chinese medicine  
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:  Shen,Linjing;  Wang,Changliang;  Chen,Liang;  Leung,Ka Lai;  Lo,Esther;  Lakso,Merja;  Wong,Garry
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C. Elegans  Lewy Body Dementia  Neurodegeneration  Parkinson's Disease  Tdp-1/tdp-43  Tdp-43  Α-synuclein  
A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
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Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6 Journal article
Brain, Behavior, and Immunity, 2020,Volume: 88,Page: 640-653
Authors:  Han，Chaojun;  Yan，Pengju;  He，Tao;  Cheng，Junjie;  Zheng，Wenhua;  Zheng，Long Tai;  Zhen，Xuechu
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Dopaminergic neuron  Microglia  Neuroinflammation  NF-κB  PHLDA1  TRAF6  Ubiquitination  
Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation Journal article
Asian Journal of Pharmaceutical Sciences, 2020,Volume: 15,Issue: 4,Page: 518-528
Authors:  Xiong，Sha;  Liu，Wei;  Zhou，Yile;  Mo，Yousheng;  Liu，Yao;  Chen，Xiaojia;  Pan，Huafeng;  Yuan，Dongsheng;  Wang，Qi;  Chen，Tongkai
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Anti-Parkinsonian efficacy  Brain permeability  Nanocrystals  Oral absorption  Resveratrol