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Gene expression data analysis using Hellinger correlation in weighted gene co-expression networks (WGCNA) Journal article
Computational Structural Biotechnology, 2022,Volume: 20,Page: 3851-3863
Authors:  Zhang, Tianjiao;  Wong, Garry
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/29
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao;  Wang, Wanhe;  Huang, Qi;  Chen, Feng;  Li, Guodong;  Wong, Chun Yuen;  Wong, Vincent Kam Wai;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:6 TC[Scopus]:8 | Submit date:2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1,Page: 1
Authors:  Shi, Lu;  An, Yongcheng;  Cheng, Long;  Li, Yiyang;  Li, Huimin;  Wang, Chen;  Lv, Yinglan;  Duan, Yuhui;  Dai, Hongyu;  He, Changhao;  Zhang, Huilin;  Huang, Yan;  Fu, Wanxin;  Wang, Shengpeng;  Zhao, Baosheng;  Wang, Yitao;  Zhao, Yonghua
Adobe PDF | Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2022/05/13
Diabetes Mellitus  Oral Ulcer  Qingwei San  Stomach Heat Syndrome  Tlr4/myd88/nf-κb  
Biomedical Analytics of Four Chinese Medicinals in Treatment of Insomnia Based on Network Pharmacology Journal article
BioMed Research International, 2022,Volume: 2022
Authors:  Deng, Qiyue;  Huang, Libing;  Yu, Fanjun;  Lin, Jiahui;  Hu, Lijuan;  Zhao, Jing;  Pan, Litao;  Kui, Yu;  Wu, Shiheng
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/05
The important herbal pair for the treatment of COVID-19 and its possible mechanisms Journal article
Chinese Medicine, 2021,Volume: 16,Issue: 1
Authors:  Xia, Shujie;  Zhong, Zhangfeng;  Gao, Bizhen;  Vong, Chi Teng;  Lin, Xuejuan;  Cai, Jin;  Gao, Hanlu;  Chan, Ging;  Li, Candong
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2021/12/09
Amygdalus Communis Vas  Association Rules  Ephedra Sinica Stapf  Herbal Pair  Molecular Docking  Network Pharmacology  Novel Coronavirus Pneumonia  
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Journal article
Bioorganic Chemistry, 2021,Volume: 114
Authors:  Yang, Guan Jun;  Song, Ying Qi;  Wang, Wanhe;  Han, Quan Bin;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/12/08
Acetylated Rela  Brd4  Nf-κb  Protein-protein Interaction  Tnbc  
Biodata Mining of Differentially Expressed Genes between Acute Myocardial Infarction and Unstable Angina Based on Integrated Bioinformatics Journal article
BioMed Research International, 2021,Volume: 2021
Authors:  Guo, Siyu;  Huang, Zhihong;  Liu, Xinkui;  Zhang, Jingyuan;  Ye, Peizhi;  Wu, Chao;  Lu, Shan;  Jia, Shanshan;  Zhang, Xiaomeng;  Chen, Xiuping;  Wang, Miaomiao;  Wu, Jiarui
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/05/13
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Genes and Diseases, 2021
Authors:  Cheng, Shasha;  Yang, Guan Jun;  Wang, Wanhe;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:6 TC[Scopus]:3 | Submit date:2022/05/13
Cancer Stem Cells  Cdk9-cyclin T1  Epithelial Mesenchymal Transition  Protein–protein Interaction (Ppi)  Triple-negative Breast Cancer (Tnbc)  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2021/03/01
Brd4  BromoDomain Domain  Cell Metastasis And Invasion  Histone Acetylation  Melanoma  Protein–protein Interaction  Virtual Screening  
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:34 | Submit date:2021/03/01
Cancer Therapy  Covalent Inhibitors  Protein-protein Interaction