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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth
Journal article
Pharmacological Research, 2022,Volume: 179
Authors:
Huang, Bin
;
Hao, Meng
;
Li, Chuwen
;
Luo, Kathy Qian
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Acetyltanshinone IIA
Afatinib (PubChem CID: 10184653)
Aurora kinase A
Drug-resistant lung cancer
EGFR
Erlotinib (PubChem CID: 176870)
LY294002 (PubChem CID: 3973)
MLN8237 (PubChem CID: 24771867)
Osimertinib (PubChem CID: 71496458)
P70S6K
PF-4708671 (PubChem CID: 51371303)
Rapamycin (PubChem CID: 5284616)
Tanshinone IIA (PubChem CID: 164676)
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer
Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:
Cheng, Sha Sha
;
Qu, Yuan Qing
;
Wu, Jia
;
Yang, Guan Jun
;
Liu, Hao
;
Wang, Wanhe
;
Huang, Qi
;
Chen, Feng
;
Li, Guodong
;
Wong, Chun Yuen
;
Wong, Vincent Kam Wai
;
Ma, Dik Lung
;
Leung, Chung Hang
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TC[WOS]:
0
TC[Scopus]:
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Submit date:2022/04/06
Epigenetics
Kinase Inhibitor
Metal Complex
Metastasis
Protein–protein Interaction
Triple-negative Breast Cancer
Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
Journal article
Medicinal Research Reviews, 2022,Volume: 42,Issue: 2,Page: 946-982
Authors:
Wang, Li
;
Li, Jiajia
;
Di, Li jun
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TC[WOS]:
1
TC[Scopus]:
2
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Submit date:2022/03/28
Energy Homeostasis
Glucose Metabolism
Gsk3
Insulin Sensitivity
Metabolic Regulators
Stress Response
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells
Journal article
Journal of Biochemical and Molecular Toxicology, 2022
Authors:
Sun, Chong
;
Zhao, Lin
;
Wang, Xianzhe
;
Hou, Ying
;
Guo, Xiuli
;
Lu, Jin Jian
;
Chen, Xiuping
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/17
Apoptosis
Colon Cancer
Jnk1/2
Psoralidin
Ros
Chromosome-level genome assembly of Welwitschia mirabilis, a unique Namib Desert species
Journal article
Molecular Ecology Resources, 2022,Volume: 22,Issue: 1,Page: 391-403
Authors:
Han, Yuwei
;
Zhang, Weixiong
;
Zhou, Botong
;
Zeng, Peng
;
Tian, Zunzhe
;
Cai, Jing
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TC[WOS]:
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TC[Scopus]:
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Submit date:2022/02/21
Chromosome-level Genome Assembly
Gene Family
Genome Evolution
Positively Selected Genes
Welwitschia Mirabilis
Whole-genome Sequencing
Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking
Journal article
Medicine (United States), 2021,Volume: 100,Issue: 51
Authors:
Li, Jialin
;
Huang, Zhihong
;
Lu, Shan
;
Luo, Hua
;
Tan, Yingying
;
Ye, Peizhi
;
Liu, Xinkui
;
Wu, Zhishan
;
Wu, Chao
;
Stalin, Antony
;
Wang, Haojia
;
Liu, Yingying
;
Shen, Liangliang
;
Fan, Xiaotian
;
Zhang, Bei
;
Yi, Jianping
;
Yao, Lu
;
Xu, Yi
;
Wu, Jiarui
;
Duan, Xianchun
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/01/14
Coronavirus Disease 2019
Molecular Docking
Molecular Mechanism
Network Pharmacology
Suhexiang Pill
A Combinatorial CRISPR–Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment
Journal article
Cancer Research, 2021,Volume: 81,Issue: 24,Page: 6219-6232
Authors:
Xu, Feng
;
Tong, Man
;
Tong, Cindy S.W.
;
Chan, Becky K.C.
;
Chu, Hoi Yee
;
Wong, Tin Lok
;
Fong, John H.C.
;
Cheung, Maggie S.H.
;
Mak, Kylie Hin Man
;
Pardeshi, Lakhansing
;
Huang, Yuanhua
;
Wong, Koon Ho
;
Choi, Gigi C.G.
;
Ma, Stephanie
;
Wong, Alan S.L.
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/11
The important herbal pair for the treatment of COVID-19 and its possible mechanisms
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Xia, Shujie
;
Zhong, Zhangfeng
;
Gao, Bizhen
;
Vong, Chi Teng
;
Lin, Xuejuan
;
Cai, Jin
;
Gao, Hanlu
;
Chan, Ging
;
Li, Candong
Favorite
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TC[WOS]:
8
TC[Scopus]:
11
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Submit date:2021/12/09
Amygdalus Communis Vas
Association Rules
Ephedra Sinica Stapf
Herbal Pair
Molecular Docking
Network Pharmacology
Novel Coronavirus Pneumonia
Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Zhou, Chunxiu
;
Zhang, Xutao
;
Ruan, Cheng Chao
;
Cheang, Wai San
Favorite
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TC[WOS]:
2
TC[Scopus]:
2
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Submit date:2021/12/09
3,3′,4,5′-tetramethoxy-trans-stilbene
3,4′,5-trimethoxy-trans-stilbene
Inflammation
Lipopolysaccharide
MAPK
NF-κB
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:
Meng, Ya
;
Song, Chengcheng
;
Ren, Zhili
;
Li, Xiaohong
;
Yang, Xiangyu
;
Ai, Nana
;
Yang, Yang
;
Wang, Dongjin
;
Zhan, Meixiao
;
Wang, Jiaxian
;
Lei, Chon Lok
;
Liu, Weiwei
;
Ge, Wei
;
Lu, Ligong
;
Chen, Guokai
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08