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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth Journal article
Pharmacological Research, 2022,Volume: 179
Authors:  Huang, Bin;  Hao, Meng;  Li, Chuwen;  Luo, Kathy Qian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
Acetyltanshinone IIA  Afatinib (PubChem CID: 10184653)  Aurora kinase A  Drug-resistant lung cancer  EGFR  Erlotinib (PubChem CID: 176870)  LY294002 (PubChem CID: 3973)  MLN8237 (PubChem CID: 24771867)  Osimertinib (PubChem CID: 71496458)  P70S6K  PF-4708671 (PubChem CID: 51371303)  Rapamycin (PubChem CID: 5284616)  Tanshinone IIA (PubChem CID: 164676)  
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao;  Wang, Wanhe;  Huang, Qi;  Chen, Feng;  Li, Guodong;  Wong, Chun Yuen;  Wong, Vincent Kam Wai;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases Journal article
Medicinal Research Reviews, 2022,Volume: 42,Issue: 2,Page: 946-982
Authors:  Wang, Li;  Li, Jiajia;  Di, Li jun
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date：2022/03/28
Energy Homeostasis  Glucose Metabolism  Gsk3  Insulin Sensitivity  Metabolic Regulators  Stress Response  
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Journal of Biochemical and Molecular Toxicology, 2022
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/17
Apoptosis  Colon Cancer  Jnk1/2  Psoralidin  Ros  
Chromosome-level genome assembly of Welwitschia mirabilis, a unique Namib Desert species Journal article
Molecular Ecology Resources, 2022,Volume: 22,Issue: 1,Page: 391-403
Authors:  Han, Yuwei;  Zhang, Weixiong;  Zhou, Botong;  Zeng, Peng;  Tian, Zunzhe;  Cai, Jing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/02/21
Chromosome-level Genome Assembly  Gene Family  Genome Evolution  Positively Selected Genes  Welwitschia Mirabilis  Whole-genome Sequencing  
Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking Journal article
Medicine (United States), 2021,Volume: 100,Issue: 51
Authors:  Li, Jialin;  Huang, Zhihong;  Lu, Shan;  Luo, Hua;  Tan, Yingying;  Ye, Peizhi;  Liu, Xinkui;  Wu, Zhishan;  Wu, Chao;  Stalin, Antony;  Wang, Haojia;  Liu, Yingying;  Shen, Liangliang;  Fan, Xiaotian;  Zhang, Bei;  Yi, Jianping;  Yao, Lu;  Xu, Yi;  Wu, Jiarui;  Duan, Xianchun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/01/14
Coronavirus Disease 2019  Molecular Docking  Molecular Mechanism  Network Pharmacology  Suhexiang Pill  
A Combinatorial CRISPR–Cas9 Screen Identifies Ifenprodil as an Adjunct to Sorafenib for Liver Cancer Treatment Journal article
Cancer Research, 2021,Volume: 81,Issue: 24,Page: 6219-6232
Authors:  Xu, Feng;  Tong, Man;  Tong, Cindy S.W.;  Chan, Becky K.C.;  Chu, Hoi Yee;  Wong, Tin Lok;  Fong, John H.C.;  Cheung, Maggie S.H.;  Mak, Kylie Hin Man;  Pardeshi, Lakhansing;  Huang, Yuanhua;  Wong, Koon Ho;  Choi, Gigi C.G.;  Ma, Stephanie;  Wong, Alan S.L.
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The important herbal pair for the treatment of COVID-19 and its possible mechanisms Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Xia, Shujie;  Zhong, Zhangfeng;  Gao, Bizhen;  Vong, Chi Teng;  Lin, Xuejuan;  Cai, Jin;  Gao, Hanlu;  Chan, Ging;  Li, Candong
Favorite |  | TC[WOS]:8 TC[Scopus]:11 | Submit date：2021/12/09
Amygdalus Communis Vas  Association Rules  Ephedra Sinica Stapf  Herbal Pair  Molecular Docking  Network Pharmacology  Novel Coronavirus Pneumonia  
Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhou, Chunxiu;  Zhang, Xutao;  Ruan, Cheng Chao;  Cheang, Wai San
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/12/09
3,3′,4,5′-tetramethoxy-trans-stilbene  3,4′,5-trimethoxy-trans-stilbene  Inflammation  Lipopolysaccharide  MAPK  NF-κB  
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:  Meng, Ya;  Song, Chengcheng;  Ren, Zhili;  Li, Xiaohong;  Yang, Xiangyu;  Ai, Nana;  Yang, Yang;  Wang, Dongjin;  Zhan, Meixiao;  Wang, Jiaxian;  Lei, Chon Lok;  Liu, Weiwei;  Ge, Wei;  Lu, Ligong;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08