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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Volume: 687,Page: 207-215
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2018/12/18
3xTg-AD mice  BV-2 cells  GSK-3β  Neuroinflammation  SLOH  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Page: 207-215
Authors:  Wu, X.;  Kosaraju, J.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/28
BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3β  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite |  | TC[WOS]:12 TC[Scopus]:12 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
Neuropharmacology, 2018,Page: 351-363
Authors:  Wu, X.;  Kosaraju, J.;  Zhou, W.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/28
Amyloid β  aggregation  Alzheimer’s disease  3xTg-AD  neuroprotection  SH-SY5Y  
Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhou, Wei;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/31
Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer’s disease drug candidates Journal article
Scientific Reports, 2017,Page: 16368 -16368
Authors:  Zhou, W.;  Hu, X.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/28
Clearance  Permeability  Pharmacokinetics-Pharmacodynamics study