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The cholesterol uptake regulator PCSK9 promotes and is a therapeutic target in APC/KRAS-mutant colorectal cancer Journal article
Nature Communications, 2022,Volume: 13,Issue: 1
Authors:  Wong, Chi Chun;  Wu, Jian Lin;  Ji, Fenfen;  Kang, Wei;  Bian, Xiqing;  Chen, Huarong;  Chan, Lam Shing;  Luk, Simson Tsz Yat;  Tong, Samuel;  Xu, Jiaying;  Zhou, Qiming;  Liu, Dabin;  Su, Hao;  Gou, Hongyan;  Cheung, Alvin Ho Kwan;  To, Ka Fai;  Cai, Zongwei;  Shay, Jerry W.;  Yu, Jun
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2023/01/30
Hyaluronic Acid-Functionalized Mesoporous Silica Nanoparticles Loading Simvastatin for Targeted Therapy of Atherosclerosis Journal article
Pharmaceutics, 2022,Volume: 14,Issue: 6
Authors:  Song, Kechen;  Tang, Zhuang;  Song, Zhiling;  Meng, Shiyu;  Yang, Xiaoxue;  Guo, Hui;  Zhu, Yizhun;  Wang, Xiaolin
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date：2023/01/30
atherosclerosis  enzyme-responsive drug release  hyaluronic acid  mesoporous silica nanoparticles  simvastatin  
Advances in Gut Microbial Drug Metabolism Journal article
药学进展 Progress in Pharmaceutical Sciences, 2020,Volume: 44,Issue: 2,Page: 83-99
Authors:  Yifei Jia;  Panpan Wang;  Yijia Chen;  Ru Yan
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/08/12
Gut Microbiota  Drug Metabolism  Host Drug Disposition  Precision Medicine  Β-glucuronidases  
Polyphenol-based nanoplatform for MRI/PET dual-modality imaging guided effective combination chemotherapy Journal article
JOURNAL OF MATERIALS CHEMISTRY B, 2019
Authors:  Jingjing Wang;  Wei Sang;  Zhen Yang;  Zheyu Shen;  Zhantong Wang;  Orit Jacobson;  Yundai Chen;  Yong Wang;  Mingyan Shao;  Gang Niu,;  Yunlu Dai;  Xiaoyuan Chen
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date：2020/05/12
Ursolic Acid Attenuates Atherosclerosis in ApoE(-/-) Mice: Role of LOX-1 Mediated by ROS/NF-B Pathway Journal article
MOLECULES, 2018,Volume: 23,Issue: 5
Authors:  Li, Qiu;  Zhao, Wenwen;  Zeng, Xi;  Hao, Zhihui
Favorite |  | TC[WOS]:22 TC[Scopus]:30 | Submit date：2018/10/30
Atherosclerosis  Ros  Huvecs  Lox-1  
Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2017,Volume: 195,Page: 118-126
Authors:  Fu, Wen-Juan;  Lei, Ting;  Yin, Zhen;  Pan, Jian-Hao;  Chai, Yu-Shuang;  Xu, Xiao-Yun;  Yan, Yi-Xi;  Wang, Zhi-Hua;  Ke, Jian;  Wu, Gang;  Xu, Ren-He;  Paranjpe, Manish;  Qu, Lintao;  Nie, Hong
Favorite |  | TC[WOS]:27 TC[Scopus]:29 | Submit date：2018/10/30
Angong Niuhuang Pill (Anp)  Atherosclerosis  High Fat Diet  Vitamin D-3  
Acute Simvastatin Inhibits KATP Channels of Porcine Coronary Artery Myocytes Journal article
PLoS ONE, 2013,Volume: 8,Issue: 6
Authors:  Sai Wang Seto;  Alice Lai Shan Au;  Christina Chui Wa Poon;  Qian Zhang;  Rachel Wai Sum Li;  John Hok Keung Yeung;  Siu Kai Kong;  Sai Ming Ngai;  Sai Ming Ngai;  Ho Pui Ho;  Simon Ming Yuen Lee;  Maggie Pui Man Hoi;  Shun Wan Chan;  George Pak Heng Leung;  Yiu Wa Kwan
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date：2018/10/30
Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats Journal article
Clinical and Experimental Pharmacology and Physiology, 2012,Volume: 39,Issue: 10,Page: 894-896
Authors:  Enoch Chan;  Janet Yuen-Yan Chan;  Jian-Hong Wu;  Chun-Wai Wan;  George Pak-Heng Leung;  Simon Ming-Yuen Lee;  Yiu-Wa Kwan;  Shun-Wan Chan
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2018/11/06
Cholesterol  Diagnostic  Nitric Oxide Synthase  Serum  Vasorelaxation  
Simvastatin protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression Journal article
Journal of Endocrinological Investigation, 2010,Volume: 33,Issue: 5,Page: 292-296
Authors:  Yao X.-M.;  Ye S.-D.;  Zai Z.;  Chen Y.;  Li X.-C.;  Yang G.-W.;  Wang Y.-X.;  Chen K.
Favorite |  | TC[WOS]:0 TC[Scopus]:26 | Submit date：2019/01/16
Diabetes mellitus  Diabetic nephropathy  Matrix metalloproteinase-9  Simvastatin  
The effect of simvastatin on the serum monocyte chemoattractant protein-1 and intracellular adhesion molecule-1 levels in diabetic rats Journal article
Journal of Diabetes and its Complications, 2009,Volume: 23,Issue: 3,Page: 214-218
Authors:  Lin Y.;  Ye S.;  Chen Y.;  Li X.;  Yang G.-w.;  Fan A.;  Wang Y.
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date：2019/01/16
Diabetes mellitus  ICAM-1  Macroangiopathy  MCP-1  Simvastatin