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Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1285-1298
Authors:  Li, Dan;  Yang, Chao;  Zhu, Jian zhong;  Lopez, Eduardo;  Zhang, Tian;  Tong, Qiang;  Peng, Cheng;  Lin, Li gen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/13
adipose tissue inflammation  berberine  fibrosis  insulin resistance  liver injury  Sirtuin 3  
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Liu, Jingxin;  Zhang, Tian;  Zhu, Jianzhong;  Ruan, Shuangchen;  Li, Rongsong;  Guo, Bing;  Lin, Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Hepatocytes  Honokiol  Lipid Accumulation  Lipolysis  Lipophagy  Sirt3  
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:18 TC[Scopus]:18 | Submit date:2021/03/01
Adipocytes  Adipose Tissue Inflammation  Autophagy  Cycloartane Triterpenoid  Il-1β, Macrophages  Macrophages  Nlrp3 Inflammasome  
Theacrine, a purine alkaloid from kucha, protects against Parkinson's disease through SIRT3 activation Journal article
Phytomedicine, 2020,Volume: 77
Authors:  Duan, Wen Jun;  Liang, Lei;  Pan, Ming Hai;  Lu, Dan Hua;  Wang, Ting Mei;  Li, Shan Bing;  Zhong, Han Bing;  Yang, Xuan Jun;  Cheng, Yan;  Liu, Bo;  Li, Wei Xi;  Kurihara, Hiroshi;  Bi, Wei;  Li, Yi Fang;  He, Rong Rong
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/12/06
Dopaminergic Neurons  Mitochondrial Dysfunction  Oxidative Damage  Parkinson's Disease  Sirt3  Theacrine  
SIRT3 acts as a positive autophagy regulator to promote lipid mobilization in adipocytes via activating AMPK Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 2
Authors:  Zhang,Tian;  Liu,Jingxin;  Tong,Qiang;  Lin,Ligen
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2021/03/01
Ampk  Chaperone-mediated Autophagy  Lipid Metabolism  Macroautophagy  Sirtuin 3  
The deacetylase SIRT3 acts as a therapeutic target against nonalcoholic fatty liver disease through adipose tissue-liver axis Project
项目类型: FDCT, 项目编号: 0031/2019/A1, 2019-
Authors:  SENGFONG
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/02/16
SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions Journal article
Autophagy, 2019,Volume: 15,Issue: 8,Page: 1356-1375
Authors:  Kim,Tae Sung;  Jin,Yeung Bae;  Kim,Yi Sak;  Kim,Sup;  Kim,Jin Kyung;  Lee,Hye Mi;  Suh,Hyun Woo;  Choe,Jin Ho;  Kim,Young Jae;  Koo,Bon Sang;  Kim,Han Na;  Jung,Mingyu;  Lee,Sang Hee;  Kim,Don Kyu;  Chung,Chaeuk;  Son,Ji Woong;  Min,Jung Joon;  Kim,Jin Man;  Deng,Chu Xia;  Kim,Hyun Seok;  Lee,Sang Rae;  Jo,Eun Kyeong
Favorite |  | TC[WOS]:37 TC[Scopus]:38 | Submit date:2020/09/16
autophagy  mitochondrial homeostasis  Mycobacterium tuberculosis  PPARA  SIRT3  
SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity Journal article
Cell Death and Differentiation, 2019,Volume: 27,Issue: 1,Page: 329-344
Authors:  Zhang,Tian;  Liu,Jingxin;  Shen,Shengnan;  Tong,Qiang;  Ma,Xiaojun;  Lin,Ligen
Favorite |  | TC[WOS]:38 TC[Scopus]:35 | Submit date:2021/03/01
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3 Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 834,Page: 176-187
Authors:  Liu, Jing-Xin;  Shen, Sheng-Nan;  Tong, Qiang;  Wang, Yi-Tao;  Lin, Li-Gen
Favorite |  | TC[WOS]:18 TC[Scopus]:18 | Submit date:2018/10/30
Honokiol  Oxidative Stress  Liver  Sirt3  Mitochondria  Fragmentation