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Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Human follicle-stimulating hormone ß subunit expression depends on FOXL2 and SMAD4 Journal article
Endocrinology (United States), 2020,Volume: 161,Issue: 5
Authors:  Ongaro,Luisina;  Schang,Gauthier;  Zhou,Ziyue;  Kumar,T. Rajendra;  Treier,Mathias;  Deng,Chu Xia;  Boehm,Ulrich;  Bernard,Daniel J.
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date:2021/03/02
Activin  FOXL2  FSH  Gonadotrope  Pituitary  SMAD4  Transgene  
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 389
Authors:  Li,Ao;  Xiao,Xiao;  Feng,Zhe Ling;  Chen,Xiuping;  Liu,Li Juan;  Lin,Li Gen;  Lu,Jin Jian;  Zhang,Le Le
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Bleomycin  Fibrotic Process  Nagilactone d  Pulmonary Fibrosis  Tgf-β1  
ROS directly activates transforming growth factor β type 1 receptor signalling in human vascular smooth muscle cells Journal article
Biochimica et Biophysica Acta - General Subjects, 2020,Volume: 1864,Issue: 1
Authors:  Mohamed,Raafat;  Cao,Yingnan;  Afroz,Rizwana;  Xu,Suowen;  Ta,Hang T.;  Barras,Michael;  Zheng,Wenhua;  Little,Peter J.;  Kamato,Danielle
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2021/03/04
Apocynin  NADPH oxidase  Reactive oxygen species  Smad2 carboxy terminal  Smooth muscle cells  Transforming growth factor β type 1 receptor  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
SMAD signaling promotes melanoma metastasis independently of phenotype switching Journal article
Journal of Clinical Investigation, 2019,Volume: 129,Issue: 7,Page: 2702-2716
Authors:  Tuncer,Eylul;  Calçada,Raquel R.;  Zingg,Daniel;  Varum,Sandra;  Cheng,Phil;  Freiberger,Sandra N.;  Deng,Chu Xia;  Kleiter,Ingo;  Levesque,Mitchell P.;  Dummer,Reinhard;  Sommer,Lukas
Favorite |  | TC[WOS]:21 TC[Scopus]:20 | Submit date:2020/09/16
Yinchenhao Decoction Alleviates Liver Fibrosis by Regulating Bile Acid Metabolism and TGF-β/Smad/ERK Signalling Pathway Journal article
Scientific Reports, 2018,Volume: 8,Issue: 1
Authors:  Cai F.-F.;  Wu R.;  Song Y.-N.;  Xiong A.-Z.;  Chen X.-L.;  Yang M.-D.;  Yang L.;  Hu Y.;  Sun M.-Y.;  Su S.-B.
Favorite |  | TC[WOS]:9 TC[Scopus]:8 | Submit date:2018/12/28