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Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong;  Yang,Xuanjun;  ShengnanLi,;  Li,Haitao;  Zhu,Qi;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lu,Jiahong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/01
Degradation  LMP7  Parkinson’s disease  Proteasome activity  α-synuclein  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2020/05/21
Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen;  Gao,Cheng;  Di,Lijun;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View | Adobe PDF | Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Tetramethylpyrazine and Paeoniflorin Inhibit Oxidized LDL-Induced Angiogenesis in Human Umbilical Vein Endothelial Cells via VEGF and Notch Pathways Journal article
Evidence-based Complementary and Alternative Medicine, 2018,Volume: 2018
Authors:  Yuan,Rong;  Shi,Weili;  Xin,Qiqi;  Yang,Binrui;  Hoi,Maggie Puiman;  Lee,Simon Mingyuan;  Cong,Weihong;  Chen,Keji
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/01
Effects of tetramethylpyrazine from Chinese black vinegar on antioxidant and hypolipidemia activities in HepG2 cells Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Chillan, CHILE, NOV 22-25, 2016
Authors:  Chen, Jicheng;  Tian, Jingjing;  Ge, Huifang;  Liu, Ruihai;  Xiao, Jianbo
Favorite |  | TC[WOS]:19 TC[Scopus]:21 | Submit date:2018/10/30
Tetramethylpyrazine  Hypolipidemic  Anti-oxidation  Cholesterol Efflux  Liver x Receptor  Peroxisome Proliferator-activated Receptor  
Effects of tetramethylpyrazine from Chinese black vinegar on antioxidant and hypolipidemia activities in HepG2 cells Journal article
Food and Chemical Toxicology, 2017,Volume: 109,Page: 930-940
Authors:  Chen J.;  Tian J.;  Ge H.;  Liu R.;  Xiao J.
Favorite |  | TC[WOS]:19 TC[Scopus]:21 | Submit date:2019/01/15
Anti-oxidation  Cholesterol efflux  Hypolipidemic  Liver X receptor  Peroxisome proliferator-activated receptor  Tetramethylpyrazine  
Synergistic effects of Chuanxiong-Chishao herb-pair on promoting angiogenesis at network pharmacological and pharmacodynamic levels Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2017,Volume: 23,Issue: 9,Page: 654-662
Authors:  Wang Yan;  Guo Gang;  Yang Bin-rui;  Xin Qi-qi;  Liao Qi-wen;  Lee Simon Ming-Yuen;  Hu Yuan-jia;  Chen Ke-jj;  Cong Wei-hong
Favorite |  | TC[WOS]:12 TC[Scopus]:13 | Submit date:2018/10/30
Tetramethylpyrazine  Paeoniflorin  Angiogenesis  Network Pharmacology  
Potent Protection Against MPP+ -Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NEUROMOLECULAR MEDICINE, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Shengquan Hu;  Liang Wang;  Shinghung Mak;  Zaijun Zhang;  Daping Xu;  Haitao Li;  Yide Li;  Yuanjia Hu;  Simon Ming Yuen Lee;  Yuqiang Wang;  Yifan Han
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2020/01/16
Parkinson’s Disease  Mef2d  Neuroprotection