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Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
8-Oxo-epiberberine  Epithelial-mesenchymal transition  Metastasis  TGF-β1  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/04
Embryonic stem cell  Peptide modification  Pluripotency  Self-renewal  Venom peptide  
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 389
Authors:  Li,Ao;  Xiao,Xiao;  Feng,Zhe Ling;  Chen,Xiuping;  Liu,Li Juan;  Lin,Li Gen;  Lu,Jin Jian;  Zhang,Le Le
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
Bleomycin  Fibrotic process  Nagilactone D  Pulmonary fibrosis  TGF-β1  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/01
EGFR mutant non-small cell lung cancer  epithelial-mesenchymal transition  NF-κB  osimertinib resistance  TGFβ2  
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts Journal article
EBioMedicine, 2019,Volume: 49,Page: 157-171
Authors:  Li,Qing;  Zhu,Chun Chao;  Ni,Bo;  Zhang,Zi Zhen;  Jiang,Shu Heng;  Hu,Li Peng;  Wang,Xu;  Zhang,Xiao Xin;  Huang,Pei Qi;  Yang,Qin;  Li,Jun;  Gu,Jian Ren;  Xu,Jia;  Luo,Kathy Qian;  Zhao,Gang;  Zhang,Zhi Gang
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2021/03/02
CAFs  Gastric cancer  Liver metastasis  LOX  Warburg effect  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Nagilactone E suppresses TGF-β1-induced epithelial–mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
Phytomedicine, 2019,Volume: 52,Page: 32-39
Authors:  Zhang L.-L.;  Jiang X.-M.;  Huang M.-Y.;  Feng Z.-L.;  Chen X.;  Wang Y.;  Li H.;  Li A.;  Lin L.-G.;  Lu J.-J.
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/12/28
Epithelial-mesenchymal transition  Nagilactone E  Smad  TGF-β1  
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Journal of Cellular Physiology, 2019,Volume: 234,Issue: 1,Page: 595-605
Authors:  Wang Q.;  Tan Q.;  Xu W.;  Kuang L.;  Zhang B.;  Wang Z.;  Ni Z.;  Su N.;  Jin M.;  Li C.;  Jiang W.;  Huang J.;  Li F.;  Zhu Y.;  Chen H.;  Du X.;  Chen D.;  Deng C.;  Qi H.;  Xie Y.;  Chen L.
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/12/13
Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling