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Canthin-6-one (CO) from Picrasma quassioides (D.Don) Benn. ameliorates lipopolysaccharide (LPS)-induced astrocyte activation and associated brain endothelial disruption Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Yue, Qian;  Xu, Yunshao;  Lin, Ligen;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Astrocyte  Blood-brain Barrier (Bbb)  Brain Endothelial Cell  Canthin-6-one (Co)  Endothelial Integrity  Neuroinflammation  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 3
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity Journal article
Chinese Medicine, 2021,Volume: 16,Issue: 1,Page: 114
Authors:  Cheng, Yaxin;  Zhao, Yonghua;  Zheng, Ying
Adobe PDF | Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/12/08
Autoimmune Diseases  Pharmacodynamics  Pharmacology  Toxicity  Triptolide  
Functionalizing Collagen with Vessel-Penetrating Two-Photon Phosphorescence Probes: A New In Vivo Strategy to Map Oxygen Concentration in Tumor Microenvironment and Tissue Ischemia Journal article
Advanced Science, 2021,Volume: 8,Issue: 20
Authors:  Wu, Cheng Ham;  Kisel, Kristina S.;  Thangavel, Muthu Kumar;  Chen, Yi Ting;  Chang, Kai Hsin;  Tsai, Ming Rung;  Chu, Chia Yu;  Shen, Yu Fang;  Wu, Pei Chun;  Zhang, Zhiming;  Liu, Tzu Ming;  Jänis, Janne;  Grachova, Elena V.;  Shakirova, Julia R.;  Tunik, Sergey P.;  Koshevoy, Igor O.;  Chou, Pi Tai
Adobe PDF | Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Phosphorescence Lifetime Imaging Microscopy  Phosphorescent Oxygen Sensors  Rei Diimine Carbonyl Complexes  Tissue Ischemia  Tumor Hypoxia  Two-photon Phosphorescence  
Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke Journal article
Phytomedicine, 2021,Volume: 90
Authors:  Liu, Bowen;  Li, Yiyang;  Han, Yan;  Wang, Shengpeng;  Yang, Hua;  Zhao, Yonghua;  Li, Ping;  Wang, Yitao
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/09/13
Acute Ischemic Stroke  Blood-brain Barrier  Caveolin1/mmp2/9 Pathway  Notoginsenoside R1  Tight Junctions  
Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Carbohydrate Polymers, 2021,Volume: 266
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding;  Chu, John M.T.;  Wong, Gordon T.C.;  Li, Juan;  Hu, Yuan Jia;  Wang, Yi Tao;  Yu, Hua
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Tetramethylpyrazine nitrone (TBN), derivative from traditional Chinese medicine Chuan Xiong exerted a protective effect on neurovascular unit against mural amyloid-beta1-42 oligomers Conference paper
Medicinal and Food Plant Research & Natural Products and Biodiversity Resources
Authors:  Qian, E.;  Hoi, P. M.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/10
TCM  neurovascular unit  amyloid beta  
Engineered exosomes: Desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies Journal article
Theranostics, 2021,Volume: 11,Issue: 18,Page: 8926-8944
Authors:  Xu, Meng;  Feng, Tao;  Liu, Bowen;  Qiu, Fen;  Xu, Youhua;  Zhao, Yonghua;  Zheng, Ying
Adobe PDF | Favorite |  | TC[WOS]:16 TC[Scopus]:17 | Submit date:2022/05/13
Administration Routes  Brain Targeting  Cerebrovascular Disease  Engineered Exosomes  Neurological Disorders  Tracking  
β-patchoulene simultaneously ameliorated dextran sulfate sodium-induced colitis and secondary liver injury in mice via suppressing colonic leakage and flora imbalance Journal article
Biochemical Pharmacology, 2020,Volume: 182
Authors:  Liu, Yuhong;  Wu, Jiazhen;  Chen, Liping;  Wu, Xue;  Gan, Yuxuan;  Xu, Nan;  Li, Minyao;  Luo, Huijuan;  Guan, Fengkun;  Su, Ziren;  Chen, Jiannan;  Li, Yucui
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2021/12/06
Colitis  Colonic Leakage  Flora Imbalance  Secondary Liver Injury  Β-patchoulene  
Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport Journal article
Journal of Ethnopharmacology, 2020,Volume: 250
Authors:  Gan, Yuxuan;  Ai, Gaoxiang;  Wu, Jiazhen;  Luo, Huijuan;  Chen, Liping;  Huang, Qionghui;  Wu, Xue;  Xu, Nan;  Li, Minyao;  Su, Ziren;  Liu, Yuhong;  Huang, Xiaoqi
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2021/12/06
5-fluorouracil  Aquaporins  Intestinal Mucositis  Patchouli Oil  Tlrs Signaling