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Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy Journal article
International Journal of Biological Macromolecules, 2022,Volume: 223,Page: 1485-1494
Authors:  Chen, Guihua;  Xiong, Wei;  Gu, Zeyun;  Gao, Yanrong;  Hou, Jiazhen;  Long, Li;  Wang, Huiyuan;  Asrorov, Akmal M.;  Muhitdinov, Bahtiyor;  Xu, Qin;  Huang, Yongzhuo
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Cancer vaccine  Engineered protein  Hydrogel  Legumain  Post-surgery  Trichosanthin  
Regulation of IFN-γ-mediated PD-L1 expression by MYC in colorectal cancer with wild-type KRAS and TP53 and its clinical implications Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Guo, Libin;  Tang, Xiaoqiong;  Wong, Sin Wa;  Guo, Anyuan;  Lin, Yao;  Kwok, Hang Fai
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Anti-pd-1/pd-l1 Cancer Therapy  Ifn-γ  Kras  Myc  Pd-l1 Expression  Tp53  
Synergistic combination of targeted nano-nuclear-reactors and anti-PD-L1 nanobodies evokes persistent T cell immune activation for cancer immunotherapy Journal article
Journal of Nanobiotechnology, 2022,Volume: 20,Issue: 1
Authors:  Zhu, Lipeng;  Li, Junnan;  Guo, Ziang;  Kwok, Hang Fai;  Zhao, Qi
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Anti-PD-L1 nanobody  Hypoxia modulation  Immune-cold tumors  Immunogenic cell death  Nano-nuclear-reactor  T cell immune activation  
Tumor PKCδ instigates immune exclusion in EGFR-mutated non–small cell lung cancer Journal article
BMC Medicine, 2022,Volume: 20,Issue: 1
Authors:  Zuo, Yi Han;  Gao, Wei Na;  Xie, Ya Jia;  Yang, Sheng Yong;  Zhou, Jin Tai;  Liang, Hai Hai;  Fan, Xing Xing
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Immune checkpoint  PD-1  PKCδ  Tumor infiltrating lymphocytes  Tumor microenvironment  
Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer Journal article
Redox Biology, 2022,Volume: 59,Page: 102578
Authors:  YinghanYan;  Fuqiang Xing;  Jiayue Cao;  Yiling Hu;  Ling Li;  Zhengyin Gao;  Hao Jia;  Kai Miao;  Fangyuan Shao;  Chu-Xia Deng;  Kathy Qian Luo;  Leo Tsz on Lee;  Tzu-Ming Liu
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Colon cancer exosome-derived biomimetic nanoplatform for curcumin-mediated sonodynamic therapy and calcium overload Journal article
Frontiers in Bioengineering and Biotechnology, 2022,Volume: 10
Authors:  Li, Yang;  Huang, Chunyu;  Xu, Youhua
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calcium carbonate  curcumin  drug delivery  exosome  sonodynamic therapy  
Tumor microenvironment adrenergic nerves blockade liposomes for cancer therapy Journal article
Journal of Controlled Release, 2022,Volume: 351,Page: 656-666
Authors:  Zhou, Shuang;  Li, Jinbo;  Yu, Jiang;  Wang, Yuequan;  Wang, Zhaomeng;  He, Zhonggui;  Ouyang, Defang;  Liu, Hongzhuo;  Wang, Yongjun
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Adrenergic Nerves  Combination Regimen  Liposome  Propranolol  Tumor Microenvironment  
Potential Focal Adhesion Kinase Inhibitors in Management of Cancer: Therapeutic Opportunities from Herbal Medicine Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 21
Authors:  Chen, Feiyu;  Zhong, Zhangfeng;  Zhang, Cheng;  Lu, Yuanjun;  Chan, Yau Tuen;  Wang, Ning;  Zhao, Di;  Feng, Yibin
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Fak  Fak Inhibitors  Metastasis  Natural Compounds  Src  Tumor  
MiR-125b-5p modulates the function of regulatory T cells in tumor microenvironment by targeting TNFR2 Journal article
Journal for ImmunoTherapy of Cancer, 2022,Volume: 10,Issue: 11
Authors:  Jiang, Mengmeng;  Yang, Yang;  Niu, Liling;  Li, Ping;  Chen, Yibo;  Liao, Ping;  Wang, Yifei;  Zheng, Jingbin;  Chen, Fengyang;  He, Huanhuan;  Li, Hui;  Chen, Xin
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Cd4-positive T-lymphocytes  Immunotherapy  Lymphocytes, Tumor-infiltrating  Tumor Microenvironment  
Complex in vitro 3D models of digestive system tumors to advance precision medicine and drug testing: Progress, challenges, and trends Journal article
Pharmacology and Therapeutics, 2022,Volume: 239
Authors:  Song, Sheng Lei;  Li, Bo;  Carvalho, Mariana R.;  Wang, Hui Jin;  Mao, De Li;  Wei, Ji Tao;  Chen, Wei;  Weng, Zhi Hui;  Chen, Yang Chao;  Deng, Chu Xia;  Reis, Rui L.;  Oliveira, Joaquim M.;  He, Yu Long;  Yan, Le Ping;  Zhang, Chang Hua
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Cancer-on-a-chip  Digestive System Cancer  In Vitro 3d Models  Organoids  Tumor Microenvironment