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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation
Journal article
Phytomedicine, 2022,Volume: 101
Authors:
Chen, Jia Yue
;
Zhu, Qi
;
Cai, Cui Zan
;
Luo, Hai Bin
;
Lu, Jia Hong
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/31
Alpha-synuclein (Α-syn)
Parkinson's Disease
Phosphodiesterase 4 Inhibitor
Protein Kinase a (Pka)
Ubiquitin-proteasome System (Ups)
USP13: Multiple Functions and Target Inhibition
Journal article
Frontiers in Cell and Developmental Biology, 2022,Volume: 10
Authors:
Li, Xiaolong
;
Yang, Ge
;
Zhang, Wenyao
;
Qin, Biying
;
Ye, Zifan
;
Shi, Huijing
;
Zhao, Xinmeng
;
Chen, Yihang
;
Song, Bowei
;
Mei, Ziqing
;
Zhao, Qi
;
Wang, Feng
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/04
Deubiquitination
Disease
Inhibitor
Structure
Ubiquitin-specific Protease 13
USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets
Journal article
Biomedicines, 2022,Volume: 10,Issue: 2
Authors:
Li, Yan Chi
;
Cai, Song Wang
;
Shu, Yu Bin
;
Chen, Mei Wan
;
Shi, Zhi
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/03/04
Cancer
Deubiquitinatase
Target
Ubiquitin
Usp15
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition
Journal article
Phytomedicine, 2022,Volume: 96
Authors:
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Senapati, Sanjib
;
Malampati, Sandeep
;
Zhu, Zhou
;
Su, Cheng Fu
;
Liu, Jia
;
Guan, Xin Jie
;
Tong, Benjamin Chun Kit
;
Cheung, King Ho
;
Tan, Jie Qiong
;
Lu, Jia Hong
;
Durairajan, Siva Sundara Kumar
;
Song, Ju Xian
;
Li, Min
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TC[WOS]:
2
TC[Scopus]:
3
|
Submit date:2022/03/04
3xtg-ad Mice
Alzheimer's Disease
Hdac6
P301s-tau Mice
Phospho-tau
Protopine
Inhibition of aberrant Hif1α activation delays intervertebral disc degeneration in adult mice
Journal article
Bone Research, 2022,Volume: 10,Issue: 1
Authors:
Wang, Zuqiang
;
Chen, Hangang
;
Tan, Qiaoyan
;
Huang, Junlan
;
Zhou, Siru
;
Luo, Fengtao
;
Zhang, Dali
;
Yang, Jing
;
Li, Can
;
Chen, Bo
;
Sun, Xianding
;
Kuang, Liang
;
Jiang, Wanling
;
Ni, Zhenhong
;
Wang, Quan
;
Chen, Shuai
;
Du, Xiaolan
;
Chen, Di
;
Deng, Chuxia
;
Yin, Liangjun
;
Chen, Lin
;
Xie, Yangli
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Dang, Yuan Ye
;
Luo, Hua
;
Li, Yong Mei
;
Zhou, Yang
;
Luo, Xiu
;
Lin, Shui Mu
;
Liu, Shou Ping
;
Lee, Simon Ming Yuen
;
Li, Chu Wen
;
Dai, Xiao Yan
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2021/12/08
Arsenic
Autophagy
Carcinogenesis
Curcumin
Gsk-3β/β-trcp
Nrf2
Ros
Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning
Journal article
Alzheimer's Research and Therapy, 2021,Volume: 13,Issue: 1
Authors:
Yuen, Sze Chung
;
Liang, Xiaonan
;
Zhu, Hongmei
;
Jia, Yongliang
;
Leung, Siu wai
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TC[WOS]:
9
TC[Scopus]:
9
|
Submit date:2021/12/09
Abmda
Alzheimer’s Disease
Biomarkers
Meta-analysis
Micrornas
Neuroinflammation
Neuronal Cell Cycle Re-entry
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo
Journal article
Pharmacological Research, 2021,Volume: 173
Authors:
Hou, Ying
;
Liu, Rong
;
Xia, Mengwei
;
Sun, Chong
;
Zhong, Bingling
;
Yu, Jie
;
Ai, Nana
;
Lu, Jin Jian
;
Ge, Wei
;
Liu, Bo
;
Chen, Xiuping
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2021/12/08
Apoptosis
Cyclin D1
G1 Cell Cycle Arrest
Nannocystin Ax
Small molecules targeting ubiquitination to control inflammatory diseases
Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 10,Page: 2414-2422
Authors:
Li, Zheng Qing
;
Chen, Xiuping
;
Wang, Ying
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TC[WOS]:
1
TC[Scopus]:
0
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Submit date:2021/12/08
Inflammatory Diseases
Small Molecule Modulator
Ubiquitin
Ubiquitination System
Full-coverage regulations of autophagy by ROS: from induction to maturation
Journal article
Autophagy, 2021
Authors:
Zhou, Jing
;
Li, Xin Yu
;
Liu, Yu Jia
;
Feng, Ji
;
Wu, Yong
;
Shen, Han Ming
;
Lu, Guo Dong
Favorite
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TC[WOS]:
8
TC[Scopus]:
6
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Submit date:2021/11/30
Atgs
Autophagy
Oxidative Regulation
Protein Thiols
Ros