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TRIM family proteins: roles in proteostasis and neurodegenerative diseases Journal article
Open Biology, 2022,Volume: 12,Issue: 8,Page: 220098
Authors:  Shim, Joong Sup
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Neurodegenerative Diseases  Trim Proteins  Protein Aggregation  Proteostasis  Ubiquitin-proteasome System  Chaperone  
α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
SARS-CoV-2 and the Nucleus Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 12,Page: 4731-4743
Authors:  Chen, Mengqi;  Ma, Yue;  Chang, Wakam
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Sars-cov-2  Nuclear Transport  Innate Immunity  Epigenetics  Cilia  Dna Damage  
Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning Journal article
Alzheimer's Research and Therapy, 2021,Volume: 13,Issue: 1
Authors:  Yuen, Sze Chung;  Liang, Xiaonan;  Zhu, Hongmei;  Jia, Yongliang;  Leung, Siu wai
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Abmda  Alzheimer’s Disease  Biomarkers  Meta-analysis  Micrornas  Neuroinflammation  Neuronal Cell Cycle Re-entry  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Phytomedicine, 2021,Volume: 87
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan;  Cai, Cui zan;  Tan, Jie qiong;  Su, Huan xing;  Lu, Jia hong
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein  
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy Journal article
Trends in Cell Biology, 2021
Authors:  Lu,Guang;  Wang,Liming;  Zhou,Jing;  Liu,Wei;  Shen,Han Ming
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Autophagy  Cancer  Cullin-ring E3 Ligases  Mtorc1  Neddylation  Ubiquitination  
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min;  Ma, Dik Lung;  Leung, Chung Hang
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Cancer  Drug Discovery  Treatment  Ubiquitination Regulator  Virtual Screening  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
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Parkinson's Disease  Α-synuclein  Degradation  Proteasome  Neuroprotection  
Organism dual RNA-seq reveals the importance of BarA/UvrY in Vibrio parahaemolyticus virulence Journal article
FASEB Journal, 2020,Volume: 34,Issue: 6,Page: 7561-7577
Authors:  Zhang W.;  Xie R.;  Zhang X.D.;  Lee L.T.O.;  Zhang H.;  Yang M.;  Peng B.;  Zheng J.
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Bara  C. Elegans  Organism Dual Rna-seq  Uvry  V. Parahaemolyticus  Virulence Factor  
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation Journal article
Phytomedicine, 2019,Volume: 61
Authors:  Cai,Cui Zan;  Zhou,He Feng;  Yuan,Ning Ning;  Wu,Ming Yue;  Lee,Simon Ming Yuen;  Ren,Jiao Yan;  Su,Huan Xing;  Lu,Jin Jian;  Chen,Xiu Ping;  Li,Min;  Tan,Jie Qiong;  Lu,Jia Hong
Favorite |  | TC[WOS]:20 TC[Scopus]:21 | Submit date:2021/03/01
-synuclein  Harmine  Parkinson's Disease  Protein Kinase a  Ubiquitin-proteasome System