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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth Journal article
Pharmacological Research, 2022,Volume: 179
Authors:  Huang, Bin;  Hao, Meng;  Li, Chuwen;  Luo, Kathy Qian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Acetyltanshinone IIA  Afatinib (PubChem CID: 10184653)  Aurora kinase A  Drug-resistant lung cancer  EGFR  Erlotinib (PubChem CID: 176870)  LY294002 (PubChem CID: 3973)  MLN8237 (PubChem CID: 24771867)  Osimertinib (PubChem CID: 71496458)  P70S6K  PF-4708671 (PubChem CID: 51371303)  Rapamycin (PubChem CID: 5284616)  Tanshinone IIA (PubChem CID: 164676)  
USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets Journal article
Biomedicines, 2022,Volume: 10,Issue: 2
Authors:  Li, Yan Chi;  Cai, Song Wang;  Shu, Yu Bin;  Chen, Mei Wan;  Shi, Zhi
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/04
Cancer  Deubiquitinatase  Target  Ubiquitin  Usp15  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/03/04
3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
Putative Factors Interfering Cell Cycle Re-Entry in Alzheimer's Disease: An Omics Study with Differential Expression Meta-Analytics and Co-Expression Profiling Journal article
Journal of Alzheimer's Disease, 2022,Volume: 85,Issue: 3,Page: 1373-1398
Authors:  Yuen, Sze Chung;  Lee, Simon Ming Yuen;  Leung, Siu Wai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Alzheimer's Disease  Cell Cycle Re-entry  Co-expression Analysis  Meta-analysis  Pagerank Algorithm  
Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2 Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Dang, Yuan Ye;  Luo, Hua;  Li, Yong Mei;  Zhou, Yang;  Luo, Xiu;  Lin, Shui Mu;  Liu, Shou Ping;  Lee, Simon Ming Yuen;  Li, Chu Wen;  Dai, Xiao Yan
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Arsenic  Autophagy  Carcinogenesis  Curcumin  Gsk-3β/β-trcp  Nrf2  Ros  
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/02
Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Small molecules targeting ubiquitination to control inflammatory diseases Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 10,Page: 2414-2422
Authors:  Li, Zheng Qing;  Chen, Xiuping;  Wang, Ying
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/12/08
Inflammatory Diseases  Small Molecule Modulator  Ubiquitin  Ubiquitination System  
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice Journal article
Environmental Pollution, 2021,Volume: 284
Authors:  Liu, Jianhui;  Li, Xiangyang;  Zhou, Guiqing;  Zhang, Yue;  Sang, Yujian;  Wang, Ji;  Li, Yanbo;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/09/17
Chromatin Remodeling  Mice  Miwi  Silica Nanoparticles  Spermatid Differentiation  Spermatogenesis  
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy Journal article
Trends in Cell Biology, 2021
Authors:  Lu,Guang;  Wang,Liming;  Zhou,Jing;  Liu,Wei;  Shen,Han Ming
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Autophagy  Cancer  Cullin-ring E3 Ligases  Mtorc1  Neddylation  Ubiquitination  
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:  Song, Ying Qi;  Wu, Chun;  Wu, Ke Jia;  Han, Quan Bin;  Miao, Xiang Min;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/12/07
Cancer  Drug Discovery  Treatment  Ubiquitination Regulator  Virtual Screening