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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth
Journal article
Pharmacological Research, 2022,Volume: 179
Authors:
Huang, Bin
;
Hao, Meng
;
Li, Chuwen
;
Luo, Kathy Qian
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Acetyltanshinone IIA
Afatinib (PubChem CID: 10184653)
Aurora kinase A
Drug-resistant lung cancer
EGFR
Erlotinib (PubChem CID: 176870)
LY294002 (PubChem CID: 3973)
MLN8237 (PubChem CID: 24771867)
Osimertinib (PubChem CID: 71496458)
P70S6K
PF-4708671 (PubChem CID: 51371303)
Rapamycin (PubChem CID: 5284616)
Tanshinone IIA (PubChem CID: 164676)
USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets
Journal article
Biomedicines, 2022,Volume: 10,Issue: 2
Authors:
Li, Yan Chi
;
Cai, Song Wang
;
Shu, Yu Bin
;
Chen, Mei Wan
;
Shi, Zhi
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/03/04
Cancer
Deubiquitinatase
Target
Ubiquitin
Usp15
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition
Journal article
Phytomedicine, 2022,Volume: 96
Authors:
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Senapati, Sanjib
;
Malampati, Sandeep
;
Zhu, Zhou
;
Su, Cheng Fu
;
Liu, Jia
;
Guan, Xin Jie
;
Tong, Benjamin Chun Kit
;
Cheung, King Ho
;
Tan, Jie Qiong
;
Lu, Jia Hong
;
Durairajan, Siva Sundara Kumar
;
Song, Ju Xian
;
Li, Min
Favorite
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TC[WOS]:
2
TC[Scopus]:
3
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Submit date:2022/03/04
3xtg-ad Mice
Alzheimer's Disease
Hdac6
P301s-tau Mice
Phospho-tau
Protopine
Putative Factors Interfering Cell Cycle Re-Entry in Alzheimer's Disease: An Omics Study with Differential Expression Meta-Analytics and Co-Expression Profiling
Journal article
Journal of Alzheimer's Disease, 2022,Volume: 85,Issue: 3,Page: 1373-1398
Authors:
Yuen, Sze Chung
;
Lee, Simon Ming Yuen
;
Leung, Siu Wai
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/17
Alzheimer's Disease
Cell Cycle Re-entry
Co-expression Analysis
Meta-analysis
Pagerank Algorithm
Curcumin prevents As3+-induced carcinogenesis through regulation of GSK3β/Nrf2
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Dang, Yuan Ye
;
Luo, Hua
;
Li, Yong Mei
;
Zhou, Yang
;
Luo, Xiu
;
Lin, Shui Mu
;
Liu, Shou Ping
;
Lee, Simon Ming Yuen
;
Li, Chu Wen
;
Dai, Xiao Yan
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2021/12/08
Arsenic
Autophagy
Carcinogenesis
Curcumin
Gsk-3β/β-trcp
Nrf2
Ros
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Wang,Anqi
;
Liu,Jiayu
;
Yang,Yuhan
;
Chen,Zhejie
;
Gao,Caifang
;
Wang,Zhanguo
;
Fu,Chaomei
;
Zou,Liang
;
Wang,Shengpeng
Favorite
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TC[WOS]:
3
TC[Scopus]:
4
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Submit date:2021/03/02
Apoptosis
Breast Cancer
Necrosis
Shikonin
Ubiquitination
Small molecules targeting ubiquitination to control inflammatory diseases
Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 10,Page: 2414-2422
Authors:
Li, Zheng Qing
;
Chen, Xiuping
;
Wang, Ying
Favorite
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TC[WOS]:
1
TC[Scopus]:
0
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Submit date:2021/12/08
Inflammatory Diseases
Small Molecule Modulator
Ubiquitin
Ubiquitination System
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice
Journal article
Environmental Pollution, 2021,Volume: 284
Authors:
Liu, Jianhui
;
Li, Xiangyang
;
Zhou, Guiqing
;
Zhang, Yue
;
Sang, Yujian
;
Wang, Ji
;
Li, Yanbo
;
Ge, Wei
;
Sun, Zhiwei
;
Zhou, Xianqing
Favorite
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TC[WOS]:
2
TC[Scopus]:
2
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Submit date:2021/09/17
Chromatin Remodeling
Mice
Miwi
Silica Nanoparticles
Spermatid Differentiation
Spermatogenesis
A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy
Journal article
Trends in Cell Biology, 2021
Authors:
Lu,Guang
;
Wang,Liming
;
Zhou,Jing
;
Liu,Wei
;
Shen,Han Ming
Favorite
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TC[WOS]:
5
TC[Scopus]:
5
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Submit date:2021/03/02
Autophagy
Cancer
Cullin-ring E3 Ligases
Mtorc1
Neddylation
Ubiquitination
Ubiquitination Regulators Discovered by Virtual Screening for the Treatment of Cancer
Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 9
Authors:
Song, Ying Qi
;
Wu, Chun
;
Wu, Ke Jia
;
Han, Quan Bin
;
Miao, Xiang Min
;
Ma, Dik Lung
;
Leung, Chung Hang
Favorite
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TC[WOS]:
2
TC[Scopus]:
1
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Submit date:2021/12/07
Cancer
Drug Discovery
Treatment
Ubiquitination Regulator
Virtual Screening