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Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes Journal article
Journal of Cellular Physiology, 2021,Volume: 236,Issue: 2,Page: 981-996
Authors:  Peng,Cheng;  Hou,Sheng Tao;  Deng,Chu Xia;  Zhang,Yandong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/02
demethylation  DHX33  Gadd45a  glycolysis  RNA helicase  Warburg effect  
Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts Journal article
EBioMedicine, 2019,Volume: 49,Page: 157-171
Authors:  Li,Qing;  Zhu,Chun Chao;  Ni,Bo;  Zhang,Zi Zhen;  Jiang,Shu Heng;  Hu,Li Peng;  Wang,Xu;  Zhang,Xiao Xin;  Huang,Pei Qi;  Yang,Qin;  Li,Jun;  Gu,Jian Ren;  Xu,Jia;  Luo,Kathy Qian;  Zhao,Gang;  Zhang,Zhi Gang
Favorite |  | TC[WOS]:17 TC[Scopus]:16 | Submit date:2021/03/02
CAFs  Gastric cancer  Liver metastasis  LOX  Warburg effect  
OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 1,Page: 179-195
Authors:  Jing Li;  Dongdong Cheng;  Miaoxin Zhu;  Huajian Yu;  Zhen Pan;  Lei Liu;  Qin Geng;  Hongyu Pan;  Mingxia Yan;  Ming Yao
Favorite |  | TC[WOS]:33 TC[Scopus]:31 | Submit date:2020/03/11
Deubiquitinating Enzyme  Otub2  Nsclc  Warburg Effect  U2af2  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 9,Page: 3012-3021
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite |  | TC[WOS]:8 TC[Scopus]:6 | Submit date:2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases Journal article
AGING AND DISEASE, 2017,Volume: 8,Issue: 3,Page: 314-333
Authors:  Cao, Yiwei;  Wang, Rui-Hong
Favorite |  | TC[WOS]:15 TC[Scopus]:13 | Submit date:2018/10/30
Age-associated diseases  circadian rhythm  metabolic reprogramming  sirtuin  tumorigenesis  Warburg effect  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:20 TC[Scopus]:20 | Submit date:2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang,Zheng;  Tam,Kin Y.
Favorite |  | TC[WOS]:20 TC[Scopus]:20 | Submit date:2021/03/04
Dichloroacetate  Drug combination  Epidermal growth factor Receptor  Erlotinib  Gefitinib  Pyruvate dehydrogenase kinase  
Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 12,Page: 1390-1400
Authors:  Wen Zhang;  Shao-Lin Zhang;  Xiaohui Hu;  Kin Yip Tam
Favorite |  | TC[WOS]:80 TC[Scopus]:83 | Submit date:2019/01/07
Aerobic Glycolysis  Pyruvate Dehydrogenase Kinases  Tumor Metabolism  Pyruvate Dehydrogenase Complex