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The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Phytomedicine, 2022,Volume: 94
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming;  Sheng, Dekuan;  Lee, Simon Ming Yuen;  Leung, George Pak Heng;  Zhou, Guo Chun;  Li, Jingjing
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Journal of Biochemical and Molecular Toxicology, 2022
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
apoptosis  colon cancer  JNK1/2  psoralidin  ROS  
Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota Journal article
Phytotherapy Research, 2022
Authors:  Dong, Lingling;  Du, Hongling;  Zhang, Minyue;  Xu, Haiting;  Pu, Xiulan;  Chen, Qiyan;  Luo, Ruifeng;  Hu, Yichen;  Wang, Yitao;  Tu, He;  Zhang, Jinming;  Gao, Fei
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
antiinflammation  gut microbiota  network pharmacology  PI3K/Akt/mTOR signaling pathway  Rhein  ulcerative colitis  
Oral colon-targeting core–shell microparticles loading curcumin for enhanced ulcerative colitis alleviating efficacy Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhang, Chen;  Chen, Zhejie;  He, Yanan;  Xian, Jing;  Luo, Ruifeng;  Zheng, Chuan;  Zhang, Jinming
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Coaxial Electrospray  Curcumin  Microparticles  Ulcerative Colitis  Zein  
A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Pharmacological Research, 2021,Volume: 173
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling;  Yu, Jie;  Ai, Nana;  Lu, Jin Jian;  Ge, Wei;  Liu, Bo;  Chen, Xiuping
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Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Anticancer effects of asiatic acid against doxorubicin-resistant breast cancer cells via an AMPK-dependent pathway in vitro Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Zhu, Zhu;  Cui, Liao;  Yang, Jing;  Vong, Chi Teng;  Hu, Yuanjia;  Xiao, Jianbo;  Chan, Ging;  He, Zhiwei;  Zhong, Zhangfeng
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Asiatic Acid  Breast Cancer  Centella Asiatica  Chemoresistance  Doxorubicin  
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65 Journal article
Phytotherapy Research, 2021,Volume: 35,Issue: 10,Page: 5861-5870
Authors:  Zhou, Yishan;  Zhong, Bingling;  Min, Xiangjing;  Hou, Ying;  Lin, Ligen;  Wu, Qin;  Shi, Jingshan;  Chen, Xiuping
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Inflammation  Isobavachalcone  Nf-κb P65  Ulcerative Colitis  
Lentinan-Based Oral Nanoparticle Loaded Budesonide With Macrophage-Targeting Ability for Treatment of Ulcerative Colitis Journal article
Frontiers in Bioengineering and Biotechnology, 2021,Volume: 9
Authors:  Lin, Meisi;  Dong, Lingling;  Chen, Qiyan;  Xu, Haiting;  Han, Xiaoqin;  Luo, Ruifeng;  Pu, Xiulan;  Qi, Shanshan;  Nie, Wenbiao;  Ma, Meilin;  Wang, Yitao;  Gao, Fei;  Zhang, Jinming
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Budesonide  Lentinan  Macrophage-target  Oral Nanoparticles  Ulcerative Colitis  
XDeep-AcPEP: Deep Learning Method for Anticancer Peptide Activity Prediction Based on Convolutional Neural Network and Multitask Learning Journal article
Journal of Chemical Information and Modeling, 2021,Volume: 61,Issue: 8,Page: 3789-3803
Authors:  Chen, Jiarui;  Cheong, Hong Hin;  Siu, Shirley W.I.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08