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Structural basis of ligand binding modes at the human formyl peptide receptor 2 Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Chen, Tong;  Xiong, Muya;  Zong, Xin;  Ge, Yunjun;  Zhang, Hui;  Wang, Mu;  Won Han, Gye;  Yi, Cuiying;  Ma, Limin;  Ye, Richard D.;  Xu, Yechun;  Zhao, Qiang;  Wu, Beili
Favorite |  | TC[WOS]:37 TC[Scopus]:34 | Submit date:2021/12/06
Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling Journal article
Pharmacological Research, 2020,Volume: 161
Authors:  Zhang, Shuo;  Gong, Hao;  Ge, Yunjun;  Ye, Richard D.
Favorite |  | TC[WOS]:10 TC[Scopus]:9 | Submit date:2021/12/06
Ac2-26: 16138723  Allosteric Modulation  Atl: 9841438  Aβ42: 71773143  Dapi: 2954  Flash: 9831137  Forskolin: 47936  g Protein-coupled Receptors  Inflammation  Lxa4: 5280914  Pertussis Toxin: 132472080  Wkymvm: 457933  Wrw4: 49768327  
Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity Journal article
FASEB Journal, 2020,Volume: 34,Issue: 5,Page: 6920-6933
Authors:  Ge,Yunjun;  Zhang,Shuo;  Wang,Junlin;  Xia,Fangbo;  Wan,Jian Bo;  Lu,Jinjian;  Ye,Richard D.
Favorite |  | TC[WOS]:26 TC[Scopus]:22 | Submit date:2021/03/02
Biased Signaling  g Protein-coupled Receptor  Inflammation  Inverse Agonism  
A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2 Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Wang, Huirong;  Peng, Xingrong;  Ge, Yunjun;  Zhang, Shuo;  Wang, Zhenyi;  Fan, Yu;  Huang, Wei;  Qiu, Minghua;  Ye, Richard D.
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/12/06
Anti-inflammatory  Chemotaxis  Fluorescence Resonance Energy Transfer  Formyl Peptide Receptors  Ganoderma  Superoxide  
FPR2 deficiency alleviates diet-induced insulin resistance through reducing body weight gain and inhibiting inflammation mediated by macrophage chemotaxis and M1 polarization Journal article
Diabetes, 2019,Volume: 68,Issue: 6,Page: 1130-1142
Authors:  Chen, Xiaofang;  Zhuo, Shu;  Zhu, Tengfei;  Yao, Pengle;  Yang, Mengmei;  Mei, Hong;  Li, Na;  Ma, Fengguang;  Wang, Ji Ming;  Chen, Shiting;  Ye, Richard D.;  Li, Yu;  Le, Yingying
Favorite |  | TC[WOS]:23 TC[Scopus]:25 | Submit date:2022/05/17
Targeted Delivery of a Ligand−Drug Conjugate via Formyl Peptide Receptor 1 through Cholesterol-Dependent Endocytosis Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 6,Page: 2636-2647
Authors:  Junlin Wang;  Meiwan Chen;  Shaoping Li;  Richard D. Ye
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2020/01/07
g Protein-coupled Receptors  Ph-sensitive Peptides Conjugates  Formyl Peptides  Receptor Internalization  Targeted Drug Delivery  
Formyl Peptide Receptor 2 Deficiency Improves Cognition and Attenuates Tau Hyperphosphorylation and Astrogliosis in a Mouse Model of Alzheimer's Disease Journal article
Journal of Alzheimer's Disease, 2019,Volume: 67,Issue: 1,Page: 169-179
Authors:  Zhang, Haibo;  Wang, Ding;  Gong, Ping;  Lin, Aihua;  Zhang, Yan;  Ye, Richard D.;  Yu, Yang
Favorite |  | TC[WOS]:14 TC[Scopus]:12 | Submit date:2022/05/23
Alzheimer's disease  astrocyte activation  formyl peptide receptor 2  tau phosphorylation  
A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2 Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 43
Authors:  Vellaisamy, Kasipandi;  Li, Guodong;  Wang, Wanhe;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:46 TC[Scopus]:47 | Submit date:2019/01/17
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View | Adobe PDF | Favorite |  | TC[WOS]:53 TC[Scopus]:50 | Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists Journal article
BIOCHEMICAL PHARMACOLOGY, 2017,Volume: 142,Page: 120-132
Authors:  Kirpotina, Liliya N.;  Schepetkin, Igor A.;  Khlebnikov, Andrei I.;  Ruban, Olga I.;  Ge, Yunjun;  Ye, Richard D.;  Kominsky, Douglas J.;  Quinn, Mark T.
Favorite |  | TC[WOS]:19 TC[Scopus]:18 | Submit date:2018/10/30
Antagonist Formyl peptide receptor  1H-pyrrol-2(5H)-one  Neutrophil  Molecular modeling