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Macrocephatriolides A and B: Two Guaianolide Trimers from Ainsliaea macrocephala as PTP1B Inhibitors and Insulin Sensitizers Journal article
Journal of Organic Chemistry, 2021,Volume: 86,Issue: 24,Page: 17782-17789
Authors:  Ren, Yong Mei;  Zhang, Rui;  Feng, Zheling;  Ke, Chang Qiang;  Yao, Sheng;  Tang, Chunping;  Lin, Ligen;  Ye, Yang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/01/14
Macrocephatrilides A and B: Two guaianolide trimers from Ainsliaea macrocephala as PTP1B inhibitors and insulin sensitizers Journal article
Journal of Organic Chemistry, 2021,Page: 17782-17789
Authors:  Feng, Z.;  Lin, L.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/27
Ainsliaea macrocephala  guaiane-type sesquiterpene lactone  PTP1B  insulin sensitivity  
Novel zebrafish polycystic kidney disease models reveal functions of the hippo pathway in renal cystogenesis Journal article
DMM Disease Models and Mechanisms, 2021,Volume: 14,Issue: 11
Authors:  Ren, Zhiqin;  Zhang, Zhiwei;  Liu, Tzu Ming;  Ge, Wei
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Hippo Signaling Pathway  Kidney Development  Polycystic Kidney Disease  Renal Cyst Formation  Zebrafish Model  
A “Bridge-Building” Glycan Scaffold Mimicking Microbial Invasion for In Situ Endothelialization Journal article
Advanced Materials, 2021,Volume: 33,Issue: 42
Authors:  Mu, Ruoyu;  Zhang, Yuhan;  Yan, Lingli;  Liao, Zhencheng;  Yang, Yushun;  Su, Huanxing;  Dong, Lei;  Wang, Chunming
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/12/08
Angiogenesis  Blood Vessels  Carbohydrates  Cell Adhesion  Natural Biomaterials  
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Genes and Diseases, 2021
Authors:  Cheng, Shasha;  Yang, Guan Jun;  Wang, Wanhe;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2022/05/13
Cancer stem cells  CDK9-cyclin T1  Epithelial mesenchymal transition  Protein–protein interaction (PPI)  Triple-negative breast cancer (TNBC)  
A Chromosome-Level Genome Assembly of Dendrobium Huoshanense Using Long Reads and Hi-C Data Journal article
Genome biology and evolution, 2020,Volume: 12,Issue: 12,Page: 2486-2490
Authors:  Han,Bangxing;  Jing,Yi;  Dai,Jun;  Zheng,Tao;  Gu,Fangli;  Zhao,Qun;  Zhu,Fucheng;  Song,Xiangwen;  Deng,Hui;  Wei,Peipei;  Song,Cheng;  Liu,Dong;  Jiang,Xueping;  Wang,Fang;  Chen,Yanjun;  Sun,Chuanbo;  Yao,Houjun;  Zhang,Li;  Chen,Naidong;  Chen,Shaotong;  Li,Xiaoli;  Wei,Yuan;  Ouyang,Zhen;  Yan,Hui;  Lu,Jiangjie;  Wang,Huizhong;  Guo,Lanping;  Kong,Lingdong;  Zhao,Jing;  Li,Shaoping;  Luo,Lifen;  Kristiansen,Karsten;  Feng,Zhan;  Sun,Silong;  Chen,Cunwu;  Yue,Zhen;  Chen,Naifu
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/01
Annotation  De Novo Assembly  Genome  Hi-c Assembly  Orchid  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
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Brd4  BromoDomain Domain  Cell Metastasis And Invasion  Histone Acetylation  Melanoma  Protein–protein Interaction  Virtual Screening  
Whole Genome Sequencing of the Blue Tilapia (Oreochromis aureus) Provides a Valuable Genetic Resource for Biomedical Research on Tilapias Journal article
Marine Drugs, 2019,Volume: 17,Issue: 7
Authors:  Bian, Chao;  Li, Jia;  Lin, Xueqiang;  Chen, Xiyang;  Yi, Yunhai;  You, Xinxin;  Zhang, Yiping;  Lv, Yunyun;  Shi, Qiong
Favorite |  | TC[WOS]:11 TC[Scopus]:10 | Submit date:2022/05/23
Antimicrobial peptide  Blue tilapia (Oreochromis aureus)  Genome annotation  Genome assembly  Whole genome sequencing  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:73 TC[Scopus]:73 | Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
View | Adobe PDF | Favorite |  | TC[WOS]:30 TC[Scopus]:30 | Submit date:2018/10/30