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TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao;  Li,Ao;  Lin,Li gen;  Li,Hua;  Lu,Jin jian
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2021/03/01
Click-it  Cmap  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Molecular Docking  Nagilactone e  Protein Synthesis Inhibitor  Riok2  Rna-seq  
Post-translational modification of KRAS: potential targets for cancer therapy Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Wang,Wei hua;  Yuan,Tao;  Qian,Mei jia;  Yan,Fang jie;  Yang,Liu;  He,Qiao jun;  Yang,Bo;  Lu,Jin jian;  Zhu,Hong
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Acetylation  Cancer Therapy  Kras  Nitrosylation  Oncogene  Palmitoylation  Phosphorylation  Post-translational Modification  Postprenylation  Prenylation  Sumoylation  Ubiquitination  
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells Journal article
Acta Pharmacologica Sinica, 2015,Volume: 36,Issue: 12,Page: 1503-1513
Authors:  Ting Li;  Xiao-huang Xu;  Zheng-hai Tang;  Ya-fang Wang;  Chung-hang Leung;  Dik-lung Ma;  Xiu-ping Chen;  Yi-tao Wang;  Yi Chen;  Jin-jian Lu
Favorite |  | TC[WOS]:37 TC[Scopus]:37 | Submit date:2018/10/31
Apoptosis  Autophagy  Erk  Baf  Bel-7402 Cells  Chloroquine  Human Hepatocellular Carcinoma  Jnk  Platycodin d  Sp600125  U0126