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Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Anti-proliferative cassane-type diterpenoids from the seeds of Caesalpinia minax Journal article
Natural Product Research, 2020
Authors:  Xu,Yunshao;  Shi,Wei;  Feng,Lu;  Cao,Jun;  Feng,Zheling;  Zhang,Qingwen;  Lu,Jinjian;  Ye,Yang;  Lin,Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Caesalpinia Minax  Cassane Diterpenoids  Cytotoxic Activity  Fabaceae  
Regulation of CD47 expression in cancer cells Journal article
Translational Oncology, 2020,Volume: 13,Issue: 12
Authors:  Huang,Can Yu;  Ye,Zi Han;  Huang,Mu Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Cd47  Cytokine  Microrna  Oncogene  Qpctl  
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2021/03/02
Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:0 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Cancer  Natural Compounds  Programmed Necrosis  
Machado-Joseph Deubiquitinases: From Cellular Functions to Potential Therapy Targets Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Zeng,Chenming;  Zhao,Chenxi;  Ge,Fujing;  Li,Yuekang;  Cao,Ji;  Ying,Meidan;  Lu,Jinjian;  He,Qiaojun;  Yang,Bo;  Dai,Xiaoyang;  Zhu,Hong
Favorite |  | TC[WOS]:2 TC[Scopus]:0 | Submit date:2021/03/02
Cancer Therapy  Cellular Functions  Deubiquitinase  Machado-joseph Domain-containing Proteases  Mjd Disease  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Identification of anti-cancer compounds from natural products Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 481-482
Authors:  LU, Jin Jian;  WANG, Yi Tao
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2021/09/13