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A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Pharmacological review of isobavachalcone, a naturally occurring chalcone Journal article
Pharmacological Research, 2021,Volume: 165
Authors:  Wang,Miaojuan;  Lin,Ligen;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Isobavachalcone  Molecular Targets  Pharmacokinetic  Pharmacology  
The development of small-molecule inhibitors targeting CD47 Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 2,Page: 561-568
Authors:  Yu,Wei Bang;  Ye,Zi Han;  Chen,Xiuping;  Shi,Jia Jie;  Lu,Jin Jian
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Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Ifn-γ  Licochalcone a  Natural Products  Pd-l1  Protein Synthesis Inhibitor  Ros  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:0 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Cancer  Natural Compounds  Programmed Necrosis  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2020,Volume: 152,Page: 336-347
Authors:  Yu, Jie;  Zhong, Bingling;  Jin, Long;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Li, Luoxiang;  Liu, Shuqin;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/09/17
Glioblastoma  Mam  Nqo1  Programmed Necrosis  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/01
Apoptosis  C-myc  Chop  Lung Cancer  Notch 3