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Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Ifn-γ  Licochalcone a  Natural Products  Pd-l1  Protein Synthesis Inhibitor  Ros  
Natural Products in Cancer Therapy: Past, Present and Future Journal article
Natural Products and Bioprospecting, 2021
Authors:  Huang,Min;  Lu,Jin Jian;  Ding,Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Antibody–drug Conjugates  Cancer Therapy  Combination Therapy  Drug Discovery  Natural Products  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Regulation of CD47 expression in cancer cells Journal article
Translational Oncology, 2020,Volume: 13,Issue: 12
Authors:  Huang,Can Yu;  Ye,Zi Han;  Huang,Mu Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Cd47  Cytokine  Microrna  Oncogene  Qpctl  
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2021/03/02
Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity Journal article
FASEB Journal, 2020,Volume: 34,Issue: 5,Page: 6920-6933
Authors:  Ge,Yunjun;  Zhang,Shuo;  Wang,Junlin;  Xia,Fangbo;  Wan,Jian Bo;  Lu,Jinjian;  Ye,Richard D.
Favorite |  | TC[WOS]:15 TC[Scopus]:14 | Submit date:2021/03/02
Biased Signaling  g Protein-coupled Receptor  Inflammation  Inverse Agonism  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao;  Li,Ao;  Lin,Li gen;  Li,Hua;  Lu,Jin jian
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2021/03/01
Click-it  Cmap  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Molecular Docking  Nagilactone e  Protein Synthesis Inhibitor  Riok2  Rna-seq