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Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 10,Page: 2511-2526
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Guan, Xin jie;  Kan, Yu xuan;  Xie, Wen jian;  Zhao, Chen liang;  Cheung, King ho;  Lu, Jia hong;  Tan, Jie qiong;  Zhang, Hong jie;  Song, Ju xian;  Li, Min
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 9,Page: 3567-3593
Authors:  Wang, Xuan;  Hua, Peng;  He, Chengwei;  Chen, Meiwan
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date:2022/05/17
Anticancer  Autophagy  Combination Therapies  Ferroptosis  Nanomedicine  Necroptosis  Non-apoptotic Cell Death  Pyroptosis  
Autophagy in health and disease: From molecular mechanisms to therapeutic target Journal article
MedComm, 2022,Volume: 3,Issue: 3
Authors:  Lu, Guang;  Wang, Yu;  Shi, Yin;  Zhang, Zhe;  Huang, Canhua;  He, Weifeng;  Wang, Chuang;  Shen, Han Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2022/10/06
Autophagy  Cancer  Cardiovascular Diseases  Metabolic Diseases  Neurodegenerative Diseases  Sars-cov-2  
Autophagy inhibition recovers deficient ICD-based cancer immunotherapy Journal article
Biomaterials, 2022,Volume: 287
Authors:  Li, Jinbo;  Cai, Wenxu;  Yu, Jiang;  Zhou, Shuang;  Li, Xianlu;  He, Zhonggui;  Ouyang, Defang;  Liu, Hongzhuo;  Wang, Yongjun
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/08/02
Atp  Autophagy Inhibitor  Immunogenic Cell Death  Liposome  Shikonin  
Chaperone-Mediated Autophagy in Neurodegenerative Diseases: Molecular Mechanisms and Pharmacological Opportunities Journal article
Cells, 2022,Volume: 11,Issue: 14
Authors:  Wang, Yi Ting;  Lu, Jia Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/08/24
Alzheimer’s Disease  Autophagy  Chaperone-mediated Autophagy  Hsc70  Huntington’s Disease  Lamp2a  Neurodegenerative Disease  Parkinson’s Disease  Small Molecule  Α-synuclein  
Chemo-Phototherapy with Carfilzomib-Encapsulated TiN Nanoshells Suppressing Tumor Growth and Lymphatic Metastasis Journal article
Small, 2022,Volume: 18,Issue: 29
Authors:  Wu, Xuan;  Wang, Le;  Xu, Yan Neng;  Chen, Jian Li;  Luo, Kathy Qian;  Yuan, Ming Heng;  Li, Jie;  Yuan, Gang;  Gu, Ze Yun;  Jia, Xiao Hui;  Chen, Xiuping;  Zhu, Xiao Ming;  Jiang, Ruibin
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/02
Autophagy  Carfilzomib  Photothermal Therapy  Proteasome Inhibitors  Tin Nanoshells  
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min;  Miao, Kai;  Lu, Jia Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou;  Su, Cheng fu;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Wu, Jia xi;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Huang, Shi ying;  Cheung, King ho;  Song, Ju xian;  Tan, Jie qiong;  Lu, Jia hong;  Li, Min
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Aging  Alzheimer’s Disease  Autophagy  Machine Learning  Mitophagy  
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:  Deng, Zhiqiang;  Dong, Yu;  Zhou, Xiaoting;  Lu, Jia Hong;  Yue, Zhenyu
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2022/05/13
Alzheimer's Disease  Autophagy  Autophagy Modulators  Genetic Modulation  Lc3-associated Phagocytosis  Microglial Autophagy  Neuroinflammation  Neuronal Autophagy