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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu,Biao;  Wang,Zhi Peng;  Liu,Qingwang;  Yang,Xiaohong;  Li,Xuemin;  Huang,Ding;  Qiu,Yanfei;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
Cancer Metabolism  Proliferation  Pyruvate Dehydrogenase Kinase  Structure-activity Relationship  
Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation Journal article
European Journal of Medicinal Chemistry, 2020,Volume: 203
Authors:  Xiang,Sichuan;  Huang,Ding;  He,Qiaolin;  Li,Jie;  Tam,Kin Yip;  Zhang,Shao Lin;  He,Yun
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Cancer Metabolism  Cancer Proliferation  Dual Inhibitor  Lactate Dehydrogenase a  Pyruvate Dehydrogenase Kinase  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine, 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/02
Ophiorrhiza Pumila  Liver Cancer  Proliferation  Apoptosis  Migration  
DNA replication licensing proteins: Saints and sinners in cancer Journal article
Seminars in Cancer Biology, 2019,Volume: 58,Page: 11-21
Authors:  Mughal,Muhammad Jameel;  Mahadevappa,Ravikiran;  Kwok,Hang Fai
Favorite |  | TC[WOS]:18 TC[Scopus]:17 | Submit date:2021/03/04
Cancer  Dna Replication  Licensing Proteins  Pre-replication Complex  Proliferation  
Warburg Effects in Cancer and Normal Proliferating Cells: Two Tales of the Same Name Journal article
Genomics, Proteomics and Bioinformatics, 2019,Volume: 17,Issue: 3,Page: 273-286
Authors:  Sun, Huiyan;  Chen, Liang;  Cao, Sha;  Liang, Yanchun;  Xu, Ying
Favorite |  | TC[WOS]:25 TC[Scopus]:27 | Submit date:2022/05/17
Cancer  Cell Proliferation  Fenton Reaction  Ph Homeostasis  Warburg Effect  
DNA replication licensing proteins: saints and sinners in cancer Journal article
Seminars in Cancer Biology, 2018,Page: -----
Authors:  Mughal, M. J.;  Mahadevappa, R.;  Kwok, H. F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/06/02
Dna Replication  Licensing Proteins  Cancer  Proliferation  Pre-replication Complex  
DNA replication licensing proteins: saints and sinners in cancer Journal article
Seminar in Cancer Biology, 2018,Page: -----
Authors:  Mughal, M. J.;  Mahadevappa, R.;  Kwok, H. F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/06/02
Dna Replication  Licensing Proteins  Cancer  Proliferation  Pre-replication Complex  
DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer Journal article
Cancers, 2018,Volume: 10,Issue: 9
Authors:  Mahadevappa R.;  Neves H.;  Yuen S.M.;  Jameel M.;  Bai Y.;  Yuen H.-F.;  Zhang S.-D.;  Zhu Y.;  Lin Y.;  Kwok H.F.
Favorite |  | TC[WOS]:20 TC[Scopus]:18 | Submit date:2018/12/19
Breast Cancer  Knockdown  Mcm10  Overexpression  Proliferation  Survival  
B-Myb Is Up-Regulated and Promotes Cell Growth and Motility in Non-Small Cell Lung Cancer Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 6
Authors:  Jin, Yuelei;  Zhu, Huifang;  Cai, Wei;  Fan, Xiaoyan;  Wang, Yitao;  Niu, Yulong;  Song, Fangzhou;  Bu, Youquan
Favorite |  | TC[WOS]:22 TC[Scopus]:22 | Submit date:2018/11/01
B-Myb  lung cancer  proliferation  migration  extracellular signal-regulated kinases (ERK)  
Preparation and evaluation of I-131-quercetin as a novel radiotherapy agent against dedifferentiated thyroid cancer Journal article
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2017,Volume: 311,Issue: 3,Page: 1697-1708
Authors:  Xie, Qinghua;  Li, Xia;  Wang, Guanquan;  Hou, Xuan;  Wang, Yujun;  Yu, Hongbo;  Qu, Changfa;  Luo, Shunzhong;  Cui, Yali;  Xia, Chuanqin;  Wang, Ruibing
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
Dedifferentiated thyroid cancer  I-131-quercetin  Proliferation inhibition  Biodistribution  Radiopharmaceutical