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Chemical Pretreatment Activated a Plastic State Amenable to Direct Lineage Reprogramming
Journal article
Frontiers in Cell and Developmental Biology, 2022,Volume: 10
Authors:
Yang, Zhenghao
;
Xu, Xiaochan
;
Gu, Chan
;
Nielsen, Alexander Valentin
;
Chen, Guokai
;
Guo, Fan
;
Tang, Chao
;
Zhao, Yang
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
cell fate transition
cell plasticity
chemical reprogramming
chromatin accessibility
direct reprogramming
Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells
Journal article
Stem Cell Research and Therapy, 2022,Volume: 13,Issue: 1
Authors:
Deng, Chunhao
;
Zhang, Zhaoying
;
Xu, Faxiang
;
Xu, Jiaqi
;
Ren, Zhili
;
Godoy-Parejo, Carlos
;
Xiao, Xia
;
Liu, Weiwei
;
Zhou, Zhou
;
Chen, Guokai
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Cell Culture
Hpscs
Pluripotency
Thyroid Hormone
Triiodothyronine (T3)
Trophoblast
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:
Meng, Ya
;
Song, Chengcheng
;
Ren, Zhili
;
Li, Xiaohong
;
Yang, Xiangyu
;
Ai, Nana
;
Yang, Yang
;
Wang, Dongjin
;
Zhan, Meixiao
;
Wang, Jiaxian
;
Lei, Chon Lok
;
Liu, Weiwei
;
Ge, Wei
;
Lu, Ligong
;
Chen, Guokai
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08
Regulation of energy metabolism in human pluripotent stem cells
Journal article
Cellular and Molecular Life Sciences, 2021,Volume: 78,Issue: 24,Page: 8097-8108
Authors:
Liu, Weiwei
;
Chen, Guokai
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08
Glycolysis
Insulin
Nutrient
Oxidative Phosphorylation
Oxygen
Ph
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells
Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:
Zhang, Yumeng
;
Xu, Jiaqi
;
Ren, Zhili
;
Meng, Ya
;
Liu, Weiwei
;
Lu, Ligong
;
Zhou, Zhou
;
Chen, Guokai
Favorite
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TC[WOS]:
5
TC[Scopus]:
4
|
Submit date:2021/12/09
Casein Kinase 1 (Ck1)
Human Embryonic Stem Cells
Kinase Inhibitor
Nicotinamide
Pancreatic Progenitors
Rho-associated Protein Kinase (Rock)
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes
Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:
Liu,Jie
;
Yang,Shuo
;
Cao,Bihui
;
Zhou,Guangyu
;
Zhang,Fengjuan
;
Wang,Yuan
;
Wang,Rixin
;
Zhu,Lipeng
;
Meng,Ya
;
Hu,Cong
;
Liang,Hui
;
Lin,Xu
;
Zhu,Kangshun
;
Chen,Guokai
;
Luo,Kathy Qian
;
Di,Lijun
;
Zhao,Qi
Favorite
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TC[WOS]:
14
TC[Scopus]:
14
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Submit date:2021/03/04
B7-h3
Bike
Bispecific Antibody
Car t
Chimeric Antigen Receptor
Non-small Cell Lung Cancer
Pd-l1
Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
Journal article
Cell Reports, 2021,Volume: 37,Issue: 9
Authors:
Xu, Faxiang
;
Deng, Chunhao
;
Ren, Zhili
;
Sun, Liangyu
;
Meng, Ya
;
Liu, Weiwei
;
Wan, Jianbo
;
Chen, Guokai
Favorite
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2021/12/08
cellular state
hPSC
lipid
LPA
metabolism
mitochondria
pluripotency
transcriptome
Protocol for intracellular and extracellular metabolite detection in human embryonic stem cells
Journal article
STAR Protocols, 2021,Volume: 2,Issue: 3
Authors:
Xu, Faxiang
;
Song, Chengcheng
;
Liu, Weiwei
;
Chen, Guokai
Favorite
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TC[WOS]:
0
TC[Scopus]:
3
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Submit date:2021/12/08
Cell culture
Cell Differentiation
Flow Cytometry/Mass Cytometry
Metabolism
Metabolomics
Stem Cells
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells
Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:
Ren,Zhili
;
Zhong,Hui
;
Song,Chengcheng
;
Deng,Chunhao
;
Hsieh,Hsun Ting
;
Liu,Weiwei
;
Chen,Guokai
Favorite
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TC[WOS]:
8
TC[Scopus]:
9
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Submit date:2021/03/02
Akt
Caspase
Cell Survival
Gsk3
Human Embryonic Stem Cells
Insulin
Mitochondrial Respiration
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening
Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:
Shao,Fangyuan
;
Lyu,Xueying
;
Miao,Kai
;
Xie,Lisi
;
Wang,Haitao
;
Xiao,Hao
;
Li,Jie
;
Chen,Qiang
;
Ding,Renbo
;
Chen,Ping
;
Xing,Fuqiang
;
Zhang,Xu
;
Luo,Guang Hui
;
Zhu,Wenli
;
Cheng,Gregory
;
Lon,Ng Wai
;
Martin,Scott E.
;
Wang,Guanyu
;
Chen,Guokai
;
Dai,Yunlu
;
Deng,Chu Xia
Favorite
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TC[WOS]:
3
TC[Scopus]:
4
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Submit date:2021/03/02
Broad Drug Resistance
Caspase 3 Activation
Patient-derived Organoid
Proteolysis
Rnai Screening