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Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9 Journal article
Experimental and Molecular Medicine, 2022
Authors:  Li, Guodong;  Li, Dan;  Wu, Chun;  Li, Shengnan;  Chen, Feng;  Li, Peng;  Ko, Chung Nga;  Wang, Wanhe;  Lee, Simon Ming Yuen;  Lin, Ligen;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/05
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao;  Wang, Wanhe;  Huang, Qi;  Chen, Feng;  Li, Guodong;  Wong, Chun Yuen;  Wong, Vincent Kam Wai;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:4 TC[Scopus]:2 | Submit date:2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1–Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury Journal article
Redox Biology, 2021,Volume: 48
Authors:  Li, Guodong;  Liu, Hao;  Feng, Ruibing;  Kang, Tian Shu;  Wang, Wanhe;  Ko, Chung Nga;  Wong, Chun Yuen;  Ye, Min;  Ma, Dik Lung;  Wan, Jian Bo;  Leung, Chung Hang
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date:2022/05/13
Inhibitor  Iridium(III) complex  Kelch-like ECH-Associated protein 1  Liver injury  Nuclear factor E2-related factor 2  
Cell imaging of dopamine receptor using agonist labeling iridium(III) complex Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 5,Page: 1119-1125
Authors:  Vellaisamy, Kasipandi;  Li, Guodong;  Ko, Chung-Nga;  Zhong, Hai-Jing;  Fatima, Sarwat;  Kwan, Hiu-Yee;  Wong, Chun-Yuen;  Kwong, Wai-Jing;  Tan, Weihong;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:95 TC[Scopus]:95 | Submit date:2018/10/30
A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 255,Page: 1953-1959
Authors:  Wang, Wanhe;  Wu, Chun;  Yang, Chao;  Li, Guodong;  Han, Quan-Bin;  Li, Shengnan;  Lee, Simon Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:23 TC[Scopus]:23 | Submit date:2018/10/30
Hydrogen Sulfide  Iridium(Iii) Complex  Sensor  Luminescence  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/10/30
Parkinson's Disease  Su4312  Neuroprotection  Myocyte Enhancer Factor 2d  Monoamine Oxidase-b  
A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation Journal article
BIOSENSORS & BIOELECTRONICS, 2017,Volume: 94,Page: 575-583
Authors:  Ko, Chung-Nga;  Yang, Chao;  Lin, Sheng;  Li, Shengnan;  Dong, Zhenzhen;  Liu, Jinbiao;  Lee, Simon Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:37 TC[Scopus]:37 | Submit date:2018/10/30
Iridum(Iii) Complex  Endogenous Sulfide Production  Sulfide Detection In livIng Organism  
A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe Journal article
NANOSCALE, 2017,Volume: 9,Issue: 14,Page: 4677-4682
Authors:  Dong, Zhen-Zhen;  Lu, Lihua;  Ko, Chung-Nga;  Yang, Chao;  Li, Shengnan;  Lee, Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
View | Adobe PDF | Favorite |  | TC[WOS]:86 TC[Scopus]:86 | Submit date:2018/10/30
A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells Journal article
JOURNAL OF MEDICINAL CHEMISTRY, 2017,Volume: 60,Issue: 6,Page: 2597-2603
Authors:  Yang, Chao;  Wang, Wanhe;  Liang, Jia-Xin;  Li, Guodong;  Vellaisamy, Kasipandi;  Wong, Chun-Yuen;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:52 TC[Scopus]:52 | Submit date:2018/10/30