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An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth
Journal article
Journal of Cancer, 2022,Volume: 13,Issue: 6,Page: 1830-1836
Authors:
Ma, Guofang
;
Tan, Chengyue
;
Shan, Yaming
;
Shao, Ningyi
;
Wang, Feng
;
Dimitrov, Dimiter S.
;
Wang, Liping
;
Zhao, Qi
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2022/05/17
Egfr
Gefitinib
Igf-i
Igf-ii
M708.5
Monoclonal Antibody
Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging
Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 53,Page: 7314-7317
Authors:
Wu, Yayun
;
Chen, Zhizhen
;
Zhang, Pengfei
;
Zhou, Lihua
;
Jiang, Tao
;
Chen, Huajie
;
Gong, Ping
;
Dimitrov, Dimiter S.
;
Cai, Lintao
;
Zhao, Qi
Favorite
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TC[WOS]:
13
TC[Scopus]:
12
|
Submit date:2018/10/30
N-terminal alpha-amino group modification of antibodies using a site-selective click chemistry method
Journal article
MABS, 2018,Volume: 10,Issue: 5,Page: 712-719
Authors:
De-zhi Li
;
Bing-nan Han
;
Rui Wei
;
Gui-yang Yao
;
Zhizhen Chen
;
Jie Liu
;
Terence C.W. Poon
;
Wu Su
;
Zhongyu Zhu
;
Dimiter S. Dimitrov
;
Qi Zhao
Favorite
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|
TC[WOS]:
18
TC[Scopus]:
19
|
Submit date:2020/06/30
Antibody
Antibody Engineering
Antibody-drug Conjugate
Click Chemistry
Site-specific Modification
Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation
Journal article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017,Volume: 485,Issue: 2,Page: 446-453
Authors:
Li, Dezhi
;
Gong, Rui
;
Zheng, Jun
;
Chen, Xihai
;
Dimitrov, Dimiter S.
;
Zhao, Qi
Favorite
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TC[WOS]:
16
TC[Scopus]:
17
|
Submit date:2018/10/30
Antibody Domain
Ch2
Nucleolin
Yeast Display
Monoclonal Antibody
Aggregation Prone Region
Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
Patent
专利号: US9150644B2, 申请日期: 2012-04-11, 公开日期: 2015-10-06
Authors:
Dimitrov, Dimiter S.
;
Zhu, Zhongyu
;
Zhao, Qi
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2022/05/21
A dual specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma
Journal article
INTERNATIONAL JOURNAL OF CANCER, 2015,Volume: 137,Issue: 9,Page: 2243-2252
Authors:
Qi Zhao
;
Hoa Tran
;
Dimiter S. Dimitrov
;
Nai-Kong V. Cheung
Favorite
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TC[WOS]:
17
TC[Scopus]:
17
|
Submit date:2019/01/23
Igf-1
Igf-2
Temsirolimus
Chemotherapy
Neuroblastoma
Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics
Journal article
MOLECULAR CANCER THERAPEUTICS, 2012,Volume: 11,Issue: 7,Page: 1400-1410
Authors:
Weizao Chen
;
Yang Feng
;
Qi Zhao
;
Zhongyu Zhu
;
Dimiter S. Dimitrov
Favorite
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TC[WOS]:
20
TC[Scopus]:
22
|
Submit date:2019/01/23
Human monoclonal antibodies to IGF1/2 with picomolar affinity
Journal article
MOLECULAR CANCER THERAPEUTICS, 2011,Volume: 10,Issue: 9,Page: 1677-1685
Authors:
Qi Zhao
;
Yang Feng
;
Zhongyu Zhu
;
Dimiter S. Dimitrov
Favorite
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TC[WOS]:
33
TC[Scopus]:
33
|
Submit date:2019/01/23
Mab
Igf2
Picomolar Affinity
Phage Display
Yeast Display
Igf1
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
Journal article
JOURNAL OF VIROLOGY, 2011,Volume: 85,Issue: 21,Page: 11401-11408
Authors:
Zhongyu Zhu
;
Haiyan Rebekah Qin
;
Weizao Chen
;
Qi Zhao
;
Xiaoying Shen
;
Robert Schutte
;
Yanping Wang
;
Gilad Ofek
;
Emily Streaker
;
Ponraj Prabakaran
;
Genevieve G. Fouda
;
Hua-Xin Liao
;
John Owens
;
Mark Louder
;
Yongping Yang
;
Kristina-Ana Klaric
;
M. Anthony Moody
;
John R. Mascola
;
Jamie K. Scott
;
Peter D. Kwong
;
David Montefiori
;
Barton F. Haynes
;
Georgia D. Tomaras
;
Dimiter S. Dimitrov
Favorite
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TC[WOS]:
70
TC[Scopus]:
74
|
Submit date:2019/01/23
Shortened Engineered Human Antibody CH2 Domains: Increased Stability and Binding to the Human Neonatal Receptor
Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011,Volume: 286,Issue: 31,Page: 27288-27293
Authors:
Rui Gong
;
Yanping Wang
;
Yang Feng
;
Qi Zhao
;
Dimiter S. Dimitrov
Favorite
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TC[WOS]:
43
TC[Scopus]:
48
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Submit date:2019/01/23