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Multiplex Single-Cell Analysis of Cancer Cells Enables Unbiased Uncovering Subsets Associated with Cancer Relapse: Heterogeneity of Multidrug Resistance in Precursor B-ALL Journal article
ChemMedChem, 2022,Volume: 17,Issue: 3
Authors:  Zhou, Ying;  Wai-Choi Tse, Eric;  Leung, Rock;  Cheung, Edwin;  Li, Hongyan;  Sun, Hongzhe
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/04
TRIM37 Augments AP-2γ Transcriptional Activity and Cellular Localization via K63-linked Ubiquitination to Drive Breast Cancer Progression Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 11,Page: 4316-4328
Authors:  Cui, Guimei;  Gao, Zhuoran;  Chang, Shiehong;  Narwade, Nitin;  Chen, Yitian;  Poudel, Barun;  Lei, Kate M.K.;  Zhang, Weibo;  Li, Gang;  Poon, Terence C.W.;  Cheung, Edwin
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/08/05
AP-2γ  breast cancer  transcriptional regulation oduction  TRIM37  
TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation Journal article
EMBO Reports, 2022
Authors:  Chen, Mi;  Lingadahalli, Shreyas;  Narwade, Nitin;  Lei, Kate Man Kei;  Liu, Shanshan;  Zhao, Zuxianglan;  Zheng, Yimin;  Lu, Qian;  Tang, Alexander Hin Ning;  Poon, Terence Chuen Wai;  Cheung, Edwin
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Androgen Signaling  Prostate Cancer  Transcriptional Regulation  Trim33  
Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression Journal article
Oncogene, 2021,Volume: 40,Issue: 47,Page: 6479-6493
Authors:  Hu, Lingling;  Chen, Xin;  Narwade, Nitin;  Lim, Michelle Gek Liang;  Chen, Zikai;  Tennakoon, Chandana;  Guan, Peiyong;  Chan, Un In;  Zhao, Zuxianglan;  Deng, Mokan;  Xu, Xiaoling;  Sung, Wing Kin;  Cheung, Edwin
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Three-dimensional folding dynamics of the Xenopus tropicalis genome Journal article
Nature Genetics, 2021,Volume: 53,Issue: 7,Page: 1075-1087
Authors:  Niu, Longjian;  Shen, Wei;  Shi, Zhaoying;  Tan, Yongjun;  He, Na;  Wan, Jing;  Sun, Jialei;  Zhang, Yuedong;  Huang, Yingzhang;  Wang, Wenjing;  Fang, Chao;  Li, Jiashuo;  Zheng, Piaopiao;  Cheung, Edwin;  Chen, Yonglong;  Li, Li;  Hou, Chunhui
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A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets Journal article
Cell Reports, 2020,Volume: 32,Issue: 6
Authors:  Zhou,Peng;  Chan,Becky K.C.;  Wan,Yuk Kei;  Yuen,Chaya T.L.;  Choi,Gigi C.G.;  Li,Xinran;  Tong,Cindy S.W.;  Zhong,Sophia S.W.;  Sun,Jieran;  Bao,Yufan;  Mak,Silvia Y.L.;  Chow,Maggie Z.Y.;  Khaw,Jien Vei;  Leung,Suet Yi;  Zheng,Zongli;  Cheung,Lydia W.T.;  Tan,Kaeling;  Wong,Koon Ho;  Chan,H. Y.Edwin;  Wong,Alan S.L.
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Cancer  Combigem  Combination Therapy  Combinatorial Genetics  Crispr  Drug Interaction  Genetic Interaction  High-throughput Screening  Neurodegeneration  Parkinson's Disease  
Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma Journal article
Cellular and Molecular Immunology, 2020,Volume: 17,Issue: 6,Page: 631-646
Authors:  Sun,Xiaoyu;  Hou,Tianheng;  Cheung,Edwin;  Iu,Tiffany Nga Teng;  Tam,Victor Wai Hou;  Chu,Ida Miu Ting;  Tsang,Miranda Sin Man;  Chan,Paul Kay Sheung;  Lam,Christopher Wai Kei;  Wong,Chun Kwok
Favorite |  | TC[WOS]:34 TC[Scopus]:35 | Submit date：2021/03/02
Allergic Asthma  Eosinophils  Il-38  Ilc2s  Tregs  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite |  | TC[WOS]:14 TC[Scopus]:20 | Submit date：2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite |  | TC[WOS]:12 TC[Scopus]:12 | Submit date：2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
An AR-ERG transcriptional signature defined by longrange chromatin interactomes in prostate cancer cells Journal article
Genome Research, 2019,Volume: 29,Issue: 2,Page: 223-235
Authors:  Zhang,Zhizhuo;  Chng,Kern Rei;  Lingadahalli,Shreyas;  Chen,Zikai;  Liu,Mei Hui;  Do,Huy Hoang;  Cai,Shaojiang;  Rinaldi,Nicola;  Poh,Huay Mei;  Li,Guoliang;  Sung,Ying Ying;  Heng,Charlie L.;  Core,Leighton J.;  Tan,Si Kee;  Ruan,Xiaoan;  Lis,John T.;  Kellis,Manolis;  Ruan,Yijun;  Sung,Wing Kin;  Cheung,Edwin
Favorite |  | TC[WOS]:21 TC[Scopus]:22 | Submit date：2021/03/02