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Natural compound glycyrrhetinic acid protects against doxorubicin-induced cardiotoxicity by activating the Nrf2/HO-1 signaling pathway Journal article
Phytomedicine, 2022,Volume: 106
Authors:  Cheng, Yanfen;  Wu, Xiaoping;  Nie, Xin;  Wu, Yihan;  Zhang, Chen;  Lee, Simon Ming Yuen;  Lv, Kongpeng;  Leung, George Pak Heng;  Fu, Chaomei;  Zhang, Jinming;  Li, Jingjing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/12/01
Cardiotoxicity  Doxorubicin  Glycyrrhetinic Acid  Nrf2  Oxidative Stress  
The role of p53 in the alternation of vascular functions Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Chan, Gabriel Hoi Huen;  Chan, Enoch;  Kwok, Carsten Tsun Ka;  Leung, George Pak Heng;  Lee, Simon Ming Yuen;  Seto, Sai Wang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/10/06
Atherosclerosis  Endothelial Dysfunction  P53  Vascular Smooth Muscle Cell  Vascular Smooth Muscle Migration  Vascular Smooth Muscle Proliferation  
An Update on the Potential Application of Herbal Medicine in Promoting Angiogenesis Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Li, Jingjing;  Li, Renkai;  Wu, Xiaoping;  Zheng, Chengwen;  Shiu, Polly Ho Ting;  Rangsinth, Panthakarn;  Lee, Simon Ming Yuen;  Leung, George Pak Heng
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/24
Herbal Medicine  Ischemic Diseases  Phytochemicals  Pro-angiogenic  Wound Healing  
The development of behavioral sensitization induced by a single morphine exposure in adult zebrafish (Danio rerio) Journal article
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022,Volume: 113
Authors:  Bian, Yaqi;  Wang, Xiufen;  Liang, Jian hui;  Li, Lin;  Wu, Xue;  Tang, Benqin;  Leung, George Pak Heng;  Lee, Simon Ming Yuen
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/03/28
Behavioral Sensitization  Drug Addiction  Morphine  Zebrafish  
Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Li, Renkai;  Mak, Winston Wing Shum;  Li, Jingjing;  Zheng, Chengwen;  Shiu, Polly Ho Ting;  Seto, Sai Wang;  Lee, Simon Ming Yuen;  Leung, George Pak Heng
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2022/05/17
Equilibrative Nucleoside Transporter  Fpmint  Inhibitor  Mechanism Of Action  Structure-activity Relationship  
The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Phytomedicine, 2022,Volume: 94
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming;  Sheng, Dekuan;  Lee, Simon Ming Yuen;  Leung, George Pak Heng;  Zhou, Guo Chun;  Li, Jingjing
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Activating Akt/mTOR and Nrf2/HO-1 Signaling Pathways Journal article
Oxidative Medicine and Cellular Longevity, 2022,Volume: 2022
Authors:  Li, Jingjing;  Cheng, Yanfen;  Li, Renkai;  Wu, Xiaoping;  Zheng, Chengwen;  Shiu, Polly Ho Ting;  Chan, Jacqueline Cho Ki;  Rangsinth, Panthakarn;  Liu, Conghui;  Leung, Susan Wai Sum;  Lee, Simon Ming Yuen;  Zhang, Chen;  Fu, Chaomei;  Zhang, Jinming;  Cheung, Timothy Man Yau;  Leung, George Pak Heng
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/08/05
Relaxation effect of narirutin on rat mesenteric arteries via nitric oxide release and activation of voltage-gated potassium channels Journal article
European Journal of Pharmacology, 2021,Volume: 905
Authors:  Wong, Emily Sze Wan;  Li, Rachel Wai Sum;  Li, Jingjing;  Li, Renkai;  Seto, Sai Wang;  Lee, Simon Ming Yuen;  Leung, George Pak Heng
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/12/08
Endothelium  Narirutin  Nitric Oxide  Relaxation  Voltage-gated Potassium Channels  
Amauroderma rugosum Protects PC12 Cells against 6-OHDA-Induced Neurotoxicity through Antioxidant and Antiapoptotic Effects Journal article
Oxidative Medicine and Cellular Longevity, 2021,Volume: 2021
Authors:  Li, Jingjing;  Li, Renkai;  Wu, Xiaoping;  Hoo, Ruby Lai Chong;  Lee, Simon Ming Yuen;  Cheung, Timothy Man Yau;  Ho, Bryan Siu Yin;  Leung, George Pak Heng
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2022/05/13
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:16 TC[Scopus]:16 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary Compound  Glycyrrhetinic Acid  Ovarian Cancer